Dementia with Lewy bodies and Parkinson’s disease dementia-two independent disorders or one clinical entity within a clinical spectrum of synucleinopathies?

Introduction: Introduction: Both dementia with Lewy bodies (DLB) and Parkinson’s disease dementia (PDD) are important dementia syndromes that overlap in their clinical features and clinical course, neuropathological abnormalities, and also therapeutic approach. Nevertheless it is still unclear wheth...

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Main Author:	Papuć Ewa
Format:	Article
Language:	deu
Published:	Sciendo 2020-09-01
Series:	Current Problems of Psychiatry
Subjects:	dementia with lewy bodies lewy body disease dementia synucleinopathies
Online Access:	https://doi.org/10.2478/cpp-2020-0015

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spelling	doaj-a4ebf77bb531431db0e88b29b32772552021-09-06T19:22:07ZdeuSciendoCurrent Problems of Psychiatry2353-86272020-09-0121316116610.2478/cpp-2020-0015Dementia with Lewy bodies and Parkinson’s disease dementia-two independent disorders or one clinical entity within a clinical spectrum of synucleinopathies?Papuć Ewa0Chair and Department of Neurology, Medical University of LublinIntroduction: Introduction: Both dementia with Lewy bodies (DLB) and Parkinson’s disease dementia (PDD) are important dementia syndromes that overlap in their clinical features and clinical course, neuropathological abnormalities, and also therapeutic approach. Nevertheless it is still unclear whether DLB and PDD are two different disorders that require differentiation or are one clinical entity within a spectrum of Lewy body disease. Currently these disorders are mainly distinguished on the basis of the relative timing of the onset of symptoms of dementia and parkinsonism. The present paper presents current concepts on the pathogenesis of both disorders and their possible overlap.https://doi.org/10.2478/cpp-2020-0015dementia with lewy bodieslewy body diseasedementiasynucleinopathies
collection	DOAJ
language	deu
format	Article
sources	DOAJ
author	Papuć Ewa
spellingShingle	Papuć Ewa Dementia with Lewy bodies and Parkinson’s disease dementia-two independent disorders or one clinical entity within a clinical spectrum of synucleinopathies? Current Problems of Psychiatry dementia with lewy bodies lewy body disease dementia synucleinopathies
author_facet	Papuć Ewa
author_sort	Papuć Ewa
title	Dementia with Lewy bodies and Parkinson’s disease dementia-two independent disorders or one clinical entity within a clinical spectrum of synucleinopathies?
title_short	Dementia with Lewy bodies and Parkinson’s disease dementia-two independent disorders or one clinical entity within a clinical spectrum of synucleinopathies?
title_full	Dementia with Lewy bodies and Parkinson’s disease dementia-two independent disorders or one clinical entity within a clinical spectrum of synucleinopathies?
title_fullStr	Dementia with Lewy bodies and Parkinson’s disease dementia-two independent disorders or one clinical entity within a clinical spectrum of synucleinopathies?
title_full_unstemmed	Dementia with Lewy bodies and Parkinson’s disease dementia-two independent disorders or one clinical entity within a clinical spectrum of synucleinopathies?
title_sort	dementia with lewy bodies and parkinson’s disease dementia-two independent disorders or one clinical entity within a clinical spectrum of synucleinopathies?
publisher	Sciendo
series	Current Problems of Psychiatry
issn	2353-8627
publishDate	2020-09-01
description	Introduction: Introduction: Both dementia with Lewy bodies (DLB) and Parkinson’s disease dementia (PDD) are important dementia syndromes that overlap in their clinical features and clinical course, neuropathological abnormalities, and also therapeutic approach. Nevertheless it is still unclear whether DLB and PDD are two different disorders that require differentiation or are one clinical entity within a spectrum of Lewy body disease. Currently these disorders are mainly distinguished on the basis of the relative timing of the onset of symptoms of dementia and parkinsonism. The present paper presents current concepts on the pathogenesis of both disorders and their possible overlap.
topic	dementia with lewy bodies lewy body disease dementia synucleinopathies
url	https://doi.org/10.2478/cpp-2020-0015
work_keys_str_mv	AT papucewa dementiawithlewybodiesandparkinsonsdiseasedementiatwoindependentdisordersoroneclinicalentitywithinaclinicalspectrumofsynucleinopathies
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Dementia with Lewy bodies and Parkinson’s disease dementia-two independent disorders or one clinical entity within a clinical spectrum of synucleinopathies?

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