Homomeric GluA2(R) AMPA receptors can conduct when desensitized
AMPA-type glutamate receptors, which mediate fast excitatory signaling throughout the brain, exhibit profound desensitization, causing a progressive current decline in the continued presence of agonist. Here authors show that homomeric Q/R edited AMPARs still allow ions to flow when the receptors ar...
Main Authors: | Ian D. Coombs, David Soto, Thomas P. McGee, Matthew G. Gold, Mark Farrant, Stuart G. Cull-Candy |
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Format: | Article |
Language: | English |
Published: |
Nature Publishing Group
2019-09-01
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Series: | Nature Communications |
Online Access: | https://doi.org/10.1038/s41467-019-12280-9 |
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