Diffusion tensor imaging and white matter abnormalities in patients with disorders of consciousness
Progress in neuroimaging has yielded new powerful tools which, potentially, can be applied to clinical populations, improve the diagnosis of neurological disorders and predict outcome. At present, the diagnosis of consciousness disorders is limited to subjective assessment and objective measurements...
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2015-01-01
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Online Access: | http://journal.frontiersin.org/Journal/10.3389/fnhum.2014.01028/full |
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doaj-a514cd1ecab7420e9fcdb4c36a166ff12020-11-25T02:19:29ZengFrontiers Media S.A.Frontiers in Human Neuroscience1662-51612015-01-01810.3389/fnhum.2014.01028112179Diffusion tensor imaging and white matter abnormalities in patients with disorders of consciousnessCarlo eCavaliere0Marco eAiello1Carol eDi Perri2Davinia eFernández-Espejo3Adrian M Owen4Andrea eSoddu5University and University Hospital of LiegeIRCCS SDN FoundationUniversity and University Hospital of LiegeUniversity of Western OntarioUniversity of Western OntarioUniversity of Western OntarioProgress in neuroimaging has yielded new powerful tools which, potentially, can be applied to clinical populations, improve the diagnosis of neurological disorders and predict outcome. At present, the diagnosis of consciousness disorders is limited to subjective assessment and objective measurements of behaviour, with an emerging role for neuroimaging techniques.In this review we focus on white matter alterations measured using Diffusion Tensor Imaging on patients with consciousness disorders, examining the most common diffusion imaging acquisition protocols and considering the main issues related to diffusion imaging analyses.We conclude by considering some of the remaining challenges to overcome, the existing knowledge gaps and the potential role of neuroimaging in understanding the pathogenesis and clinical features of disorders of consciousness.http://journal.frontiersin.org/Journal/10.3389/fnhum.2014.01028/fullBrainComaConsciousnessDiffusion Tensor Imagingtractography |
collection |
DOAJ |
language |
English |
format |
Article |
sources |
DOAJ |
author |
Carlo eCavaliere Marco eAiello Carol eDi Perri Davinia eFernández-Espejo Adrian M Owen Andrea eSoddu |
spellingShingle |
Carlo eCavaliere Marco eAiello Carol eDi Perri Davinia eFernández-Espejo Adrian M Owen Andrea eSoddu Diffusion tensor imaging and white matter abnormalities in patients with disorders of consciousness Frontiers in Human Neuroscience Brain Coma Consciousness Diffusion Tensor Imaging tractography |
author_facet |
Carlo eCavaliere Marco eAiello Carol eDi Perri Davinia eFernández-Espejo Adrian M Owen Andrea eSoddu |
author_sort |
Carlo eCavaliere |
title |
Diffusion tensor imaging and white matter abnormalities in patients with disorders of consciousness |
title_short |
Diffusion tensor imaging and white matter abnormalities in patients with disorders of consciousness |
title_full |
Diffusion tensor imaging and white matter abnormalities in patients with disorders of consciousness |
title_fullStr |
Diffusion tensor imaging and white matter abnormalities in patients with disorders of consciousness |
title_full_unstemmed |
Diffusion tensor imaging and white matter abnormalities in patients with disorders of consciousness |
title_sort |
diffusion tensor imaging and white matter abnormalities in patients with disorders of consciousness |
publisher |
Frontiers Media S.A. |
series |
Frontiers in Human Neuroscience |
issn |
1662-5161 |
publishDate |
2015-01-01 |
description |
Progress in neuroimaging has yielded new powerful tools which, potentially, can be applied to clinical populations, improve the diagnosis of neurological disorders and predict outcome. At present, the diagnosis of consciousness disorders is limited to subjective assessment and objective measurements of behaviour, with an emerging role for neuroimaging techniques.In this review we focus on white matter alterations measured using Diffusion Tensor Imaging on patients with consciousness disorders, examining the most common diffusion imaging acquisition protocols and considering the main issues related to diffusion imaging analyses.We conclude by considering some of the remaining challenges to overcome, the existing knowledge gaps and the potential role of neuroimaging in understanding the pathogenesis and clinical features of disorders of consciousness. |
topic |
Brain Coma Consciousness Diffusion Tensor Imaging tractography |
url |
http://journal.frontiersin.org/Journal/10.3389/fnhum.2014.01028/full |
work_keys_str_mv |
AT carloecavaliere diffusiontensorimagingandwhitematterabnormalitiesinpatientswithdisordersofconsciousness AT marcoeaiello diffusiontensorimagingandwhitematterabnormalitiesinpatientswithdisordersofconsciousness AT carolediperri diffusiontensorimagingandwhitematterabnormalitiesinpatientswithdisordersofconsciousness AT daviniaefernandezespejo diffusiontensorimagingandwhitematterabnormalitiesinpatientswithdisordersofconsciousness AT adrianmowen diffusiontensorimagingandwhitematterabnormalitiesinpatientswithdisordersofconsciousness AT andreaesoddu diffusiontensorimagingandwhitematterabnormalitiesinpatientswithdisordersofconsciousness |
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1724876507312029696 |