Activation of Galectin-3 (LGALS3) Transcription by Injurious Stimuli in the Liver Is Commonly Mediated by BRG1

Activation of Galectin-3 (LGALS3) Transcription by Injurious Stimuli in the Liver Is Commonly Mediated by BRG1

Galectin-3 (encoded by LGALS3) is a glycan-binding protein that regulates a diverse range of pathophysiological processes contributing to the pathogenesis of human diseases. Previous studies have found that galectin-3 levels are up-regulated in the liver by a host of different injurious stimuli. The...

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Bibliographic Details
Main Authors: Zilong Li, Fangqiao Lv, Congxin Dai, Qiong Wang, Chao Jiang, Mingming Fang, Yong Xu
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-11-01
Series:Frontiers in Cell and Developmental Biology
Subjects:
transcriptional regulation
epigenetics
liver injury
hepatocytes
DNA demethylation
Online Access:https://www.frontiersin.org/article/10.3389/fcell.2019.00310/full

Internet

https://www.frontiersin.org/article/10.3389/fcell.2019.00310/full

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