Functional disruption of the Golgi apparatus protein ARF1 sensitizes MDA-MB-231 breast cancer cells to the antitumor drugs Actinomycin D and Vinblastine through ERK and AKT signaling.
Increasing evidence indicates that the Golgi apparatus plays active roles in cancer, but a comprehensive understanding of its functions in the oncogenic transformation has not yet emerged. At the same time, the Golgi is becoming well recognized as a hub that integrates its functions of protein and l...
Main Authors: | Charlotte Luchsinger, Marcelo Aguilar, Patricia V Burgos, Pamela Ehrenfeld, Gonzalo A Mardones |
---|---|
Format: | Article |
Language: | English |
Published: |
Public Library of Science (PLoS)
2018-01-01
|
Series: | PLoS ONE |
Online Access: | http://europepmc.org/articles/PMC5882166?pdf=render |
Similar Items
-
Distinct Biochemical Pools of Golgi Phosphoprotein 3 in the Human Breast Cancer Cell Lines MCF7 and MDA-MB-231.
by: María J Tenorio, et al.
Published: (2016-01-01) -
Potential Effects of Chrysin on MDA-MB-231 Cells
by: Maimunah Ahmad, et al.
Published: (2010-03-01) -
Antitumor Activity of Chinese Propolis in Human Breast Cancer MCF-7 and MDA-MB-231 Cells
by: Hongzhuan Xuan, et al.
Published: (2014-01-01) -
Shock wave impact on the viability of MDA-MB-231 cells.
by: Yingqian Liao, et al.
Published: (2020-01-01) -
Citral induced apoptosis in MDA-MB-231 spheroid cells
by: Siyamak Ebrahimi Nigjeh, et al.
Published: (2018-02-01)