An Analysis of Treatment and Prognosis of Spinal Tuberculosis: A Prospective Study done in Tertiary Care Centre

• Main Authors: Shubhendu Gupta, Harsh Pratap Shishodia, Varun Singh
• Format: Article
• Language: English
• Published: JCDR Research and Publications Private Limited 2020-06-01
• Series: Journal of Clinical and Diagnostic Research
• Subjects: anti-tuberculosis therapy; pott’s disease; spinal cord
• Online Access: https://jcdr.net/articles/PDF/13785/44701_CE[Ra1]_F(SHU)_PF1(AG_KM)_PFA(SL)_PB(AG_SHU)_GC(SHU)_PN(SL).pdf

ABSTRACT Introduction: In cases of skeletal Tuberculosis (TB), spinal TB is considered to be the most hazardous. Early treatment of spinal TB brings somewhat fine projections as well. Aim: To evaluate the treatment and prognosis of patients with spinal TB. Materials and Methods: The study involved patients with spinal TB from the period of 2017 to 2019. The total of 67 patients were included and follow-ups were made during the entire period of healing. Patients diagnosed with spinal TB and had not previously received anti-TB therapy and debridement or radical decompression surgery were included. A paired t-test was used to compare the pre-treatment and post-treatment clinical data. A p-value <0.05 was considered statistically significant. Results: The male patients comprised of the 62.7% of the total sample size. At the final follow-up, the Visual Analogue Scale (VAS) score significantly improved from 5.99±2.11 preoperatively to 1.90±4.81 postoperatively (0<0.05), the Cobb angle significantly decreased from 16.84±6.42 preoperatively to 3.86±2.26 postoperatively (0<0.05). The Erythrocyte Sedimentation Rate (ESR) significantly decreased from 45.26±12.26 preoperatively to 9.91±6.48 postoperatively (0<0.05), and C-Reactive Protein (CRP) also significantly decreased from 49.22±42.31 to 9.84±11.53. Conclusion: Quick treatment and diagnosis of spinal TB are essential to prevent permanent neurological disability and to minimise spinal deformity.