Variation in the observed effect of Xpert MTB/RIF testing for tuberculosis on mortality: A systematic review and analysis of trial design considerations [version 2; peer review: 2 approved]

Variation in the observed effect of Xpert MTB/RIF testing for tuberculosis on mortality: A systematic review and analysis of trial design considerations [version 2; peer review: 2 approved]

Background: Most studies evaluating the effect of Xpert MTB/RIF testing for tuberculosis (TB) concluded that it did not reduce overall mortality compared to usual care. We conducted a systematic review to assess whether key study design and execution features contributed to earlier identification of...

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Bibliographic Details
Main Authors: Eleanor A. Ochodo, Nelson Kalema, Samuel Schumacher, Karen Steingart, Taryn Young, Susan Mallett, Jon Deeks, Frank Cobelens, Patrick M. Bossuyt, Mark P. Nicol, Adithya Cattamanchi
Format: Article
Language:English
Published: Wellcome 2020-08-01
Series:Wellcome Open Research
Online Access:https://wellcomeopenresearch.org/articles/4-173/v2

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