Robust innate responses to SARS-CoV-2 in children resolve faster than in adults without compromising adaptive immunity
Summary: SARS-CoV-2 infection in children is less severe than it is in adults. We perform a longitudinal analysis of the early innate responses in children and adults with mild infection within household clusters. Children display fewer symptoms than adults do, despite similar initial viral load, an...
Main Authors: | Maria Vono, Angela Huttner, Sylvain Lemeille, Paola Martinez-Murillo, Benjamin Meyer, Stephanie Baggio, Shilpee Sharma, Anais Thiriard, Arnaud Marchant, Gert-Jan Godeke, Chantal Reusken, Catia Alvarez, Francisco Perez-Rodriguez, Isabella Eckerle, Laurent Kaiser, Natasha Loevy, Christiane S. Eberhardt, Geraldine Blanchard-Rohner, Claire-Anne Siegrist, Arnaud M. Didierlaurent |
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Format: | Article |
Language: | English |
Published: |
Elsevier
2021-10-01
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Series: | Cell Reports |
Subjects: | |
Online Access: | http://www.sciencedirect.com/science/article/pii/S2211124721012274 |
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