Are AMPA Receptor Positive Allosteric Modulators Potential Pharmacotherapeutics for Addiction?
Positive allosteric modulators (PAMs) of α-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid (AMPA) receptors are a diverse class of compounds that increase fast excitatory transmission in the brain. AMPA PAMs have been shown to facilitate long-term potentiation, strengthen communication between v...
Main Authors: | Lucas R. Watterson, M. Foster Olive |
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Format: | Article |
Language: | English |
Published: |
MDPI AG
2013-12-01
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Series: | Pharmaceuticals |
Subjects: | |
Online Access: | http://www.mdpi.com/1424-8247/7/1/29 |
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