Reversible Oxidation of Myometrial Voltage-Gated Potassium Channels with Hydrogen Peroxide

The uteri, spontaneously active or Ca2+ (6 mM) induced, were allowed to equilibrate, and to inhibit voltage-gated potassium () channels 1 mM 4-amino pyridine (4-AP) was applied for 15 min before adding H2O2 .  H2O2 was added cumulatively: 2 μM, 20 μM, 200 μM, 400 μM, and 3 mM. Average time for H2O2...

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Bibliographic Details
Main Authors: Isabella Appiah, Aleksandra Nikolic-Kokic, Zorana Orescanin-Dusic, Ratko Radojicic, Slobodan Milovanovic, Mihajlo Spasic, Dusko Blagojevic
Format: Article
Published: Hindawi Limited 2012-01-01
Series:Oxidative Medicine and Cellular Longevity
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