Insulin Secretory Capacity and Insulin Resistance in Korean Type 2 Diabetes Mellitus Patients
It is well known that many Korean patients with type 2 diabetes mellitus (T2DM) were non-obese and had decreased insulin secretion in past. However, during the past three decades, lifestyles in Korea have been westernized. As a result, the prevalence of obesity, the main cause of diabetes has increa...
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doaj-a5c66d2465834adbbf0399feb5c24ca22020-11-24T22:27:15ZengAcademya Publishing Co.Endocrinology and Metabolism2093-596X2093-59782016-09-0131335436010.3803/EnM.2016.31.3.35420234Insulin Secretory Capacity and Insulin Resistance in Korean Type 2 Diabetes Mellitus PatientsJong-Dai KimWon-Young LeeIt is well known that many Korean patients with type 2 diabetes mellitus (T2DM) were non-obese and had decreased insulin secretion in past. However, during the past three decades, lifestyles in Korea have been westernized. As a result, the prevalence of obesity, the main cause of diabetes has increased. Thus, there is still a question as to whether the main pathophysiology of current Korean T2DM is insulin resistance or an insulin secretion defect. Because various anti-diabetes medications having different mechanisms of action are currently used as therapeutics, it is important to understand which of these factors is the main physiology in the development of diabetes in Koreans. In this review, we review changes in obesity prevalence, insulin resistance and insulin secretion defects in Korean T2DM during three decades.http://e-enm.org/Synapse/Data/PDFData/2008ENM/enm-31-354.pdfInsulin resistanceDiabetes mellitus, type 2Asian continental ancestry group |
collection |
DOAJ |
language |
English |
format |
Article |
sources |
DOAJ |
author |
Jong-Dai Kim Won-Young Lee |
spellingShingle |
Jong-Dai Kim Won-Young Lee Insulin Secretory Capacity and Insulin Resistance in Korean Type 2 Diabetes Mellitus Patients Endocrinology and Metabolism Insulin resistance Diabetes mellitus, type 2 Asian continental ancestry group |
author_facet |
Jong-Dai Kim Won-Young Lee |
author_sort |
Jong-Dai Kim |
title |
Insulin Secretory Capacity and Insulin Resistance in Korean Type 2 Diabetes Mellitus Patients |
title_short |
Insulin Secretory Capacity and Insulin Resistance in Korean Type 2 Diabetes Mellitus Patients |
title_full |
Insulin Secretory Capacity and Insulin Resistance in Korean Type 2 Diabetes Mellitus Patients |
title_fullStr |
Insulin Secretory Capacity and Insulin Resistance in Korean Type 2 Diabetes Mellitus Patients |
title_full_unstemmed |
Insulin Secretory Capacity and Insulin Resistance in Korean Type 2 Diabetes Mellitus Patients |
title_sort |
insulin secretory capacity and insulin resistance in korean type 2 diabetes mellitus patients |
publisher |
Academya Publishing Co. |
series |
Endocrinology and Metabolism |
issn |
2093-596X 2093-5978 |
publishDate |
2016-09-01 |
description |
It is well known that many Korean patients with type 2 diabetes mellitus (T2DM) were non-obese and had decreased insulin secretion in past. However, during the past three decades, lifestyles in Korea have been westernized. As a result, the prevalence of obesity, the main cause of diabetes has increased. Thus, there is still a question as to whether the main pathophysiology of current Korean T2DM is insulin resistance or an insulin secretion defect. Because various anti-diabetes medications having different mechanisms of action are currently used as therapeutics, it is important to understand which of these factors is the main physiology in the development of diabetes in Koreans. In this review, we review changes in obesity prevalence, insulin resistance and insulin secretion defects in Korean T2DM during three decades. |
topic |
Insulin resistance Diabetes mellitus, type 2 Asian continental ancestry group |
url |
http://e-enm.org/Synapse/Data/PDFData/2008ENM/enm-31-354.pdf |
work_keys_str_mv |
AT jongdaikim insulinsecretorycapacityandinsulinresistanceinkoreantype2diabetesmellituspatients AT wonyounglee insulinsecretorycapacityandinsulinresistanceinkoreantype2diabetesmellituspatients |
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