Effects of domestic solid fuel combustion emissions on the biomarkers of homemakers in rural areas of the Fenwei Plain, China
Background: The health effects of heavy solid fuel use in winter in rural China are of concern. The effects of air pollution resulting from domestic solid fuel combustion in rural households on rural homemakers’ biomarkers were revealed in this study. Methods: In total, 75 female homemakers from rur...
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doaj-a5efd9afc43743b4aa802afebf1bfde12021-04-23T06:16:48ZengElsevierEcotoxicology and Environmental Safety0147-65132021-05-01214112104Effects of domestic solid fuel combustion emissions on the biomarkers of homemakers in rural areas of the Fenwei Plain, ChinaRong Feng0Hongmei Xu1Kailai He2Zexuan Wang3Bei Han4Ronghui Lei5Kin Fai Ho6Xinyi Niu7Jian Sun8Bin Zhang9Pingping Liu10Zhenxing Shen11Department of Environmental Science and Engineering, Xi’an Jiaotong University, Xi’an, ChinaDepartment of Environmental Science and Engineering, Xi’an Jiaotong University, Xi’an, China; Corresponding author.Department of Environmental Science and Engineering, Xi’an Jiaotong University, Xi’an, ChinaDepartment of Environmental Science and Engineering, Xi’an Jiaotong University, Xi’an, ChinaSchool of Public Health, Health Science Center, Xi’an Jiaotong University, Xi’an, ChinaSchool of Public Health, Health Science Center, Xi’an Jiaotong University, Xi’an, ChinaJC School of Public Health and Primary Care, The Chinese University of Hong Kong, Hong Kong, ChinaSchool of Human Settlements and Civil Engineering, Xi’an Jiaotong University, Xi’an, ChinaDepartment of Environmental Science and Engineering, Xi’an Jiaotong University, Xi’an, ChinaDepartment of Environmental Science and Engineering, Xi’an Jiaotong University, Xi’an, ChinaDepartment of Environmental Science and Engineering, Xi’an Jiaotong University, Xi’an, ChinaDepartment of Environmental Science and Engineering, Xi’an Jiaotong University, Xi’an, ChinaBackground: The health effects of heavy solid fuel use in winter in rural China are of concern. The effects of air pollution resulting from domestic solid fuel combustion in rural households on rural homemakers’ biomarkers were revealed in this study. Methods: In total, 75 female homemakers from rural areas of Guanzhong Basin, the Fenwei Plain, People’s Republic of China, were randomly selected and divided into three groups (biomass users, coal users, and nonusers of solid fuel user [control group]). The differences in biological indicators, including 8-hydrox-2′-deoxyguanosine (8-OHdG), interlukin-6 (IL-6), and tumor necrosis factor-alpha (TNF-α) in urine samples as well as blood pressure (BP, including systolic BP [SBP] and diastolic BP [DBP]) and heart rate (HR) among the groups in winter and summer were investigated using statistical analysis. Results: IL-6, 8-OHdG, HR, SBP, and DBP were significantly higher in winter than in summer (P < 0.05) owing to the poor air quality resulted from the excessive use of solid fuels in winter. Significant seasonal differences in 8-OHdG were observed for both coal and biomass users. After the influence of confounders was removed, only IL-6 levels in the urine of solid fuel users were significantly higher than that of the control group. Conclusions: IL-6 is a sensitive biomarker representing inflammatory responses to particulate matter emitted through household solid fuel combustion. Locally, excessive use of solid fuels in winter posed serious PM2.5 pollution in this area and adverse effects on inflammatory biomarkers in these rural homemakers and induced DNA damage related to oxidative stress.http://www.sciencedirect.com/science/article/pii/S0147651321002153Solid fuel combustionBiomarkerHealth effectRural householdFenwei Plain |
collection |
DOAJ |
language |
English |
format |
Article |
sources |
DOAJ |
author |
Rong Feng Hongmei Xu Kailai He Zexuan Wang Bei Han Ronghui Lei Kin Fai Ho Xinyi Niu Jian Sun Bin Zhang Pingping Liu Zhenxing Shen |
spellingShingle |
Rong Feng Hongmei Xu Kailai He Zexuan Wang Bei Han Ronghui Lei Kin Fai Ho Xinyi Niu Jian Sun Bin Zhang Pingping Liu Zhenxing Shen Effects of domestic solid fuel combustion emissions on the biomarkers of homemakers in rural areas of the Fenwei Plain, China Ecotoxicology and Environmental Safety Solid fuel combustion Biomarker Health effect Rural household Fenwei Plain |
author_facet |
Rong Feng Hongmei Xu Kailai He Zexuan Wang Bei Han Ronghui Lei Kin Fai Ho Xinyi Niu Jian Sun Bin Zhang Pingping Liu Zhenxing Shen |
author_sort |
Rong Feng |
title |
Effects of domestic solid fuel combustion emissions on the biomarkers of homemakers in rural areas of the Fenwei Plain, China |
title_short |
Effects of domestic solid fuel combustion emissions on the biomarkers of homemakers in rural areas of the Fenwei Plain, China |
title_full |
Effects of domestic solid fuel combustion emissions on the biomarkers of homemakers in rural areas of the Fenwei Plain, China |
title_fullStr |
Effects of domestic solid fuel combustion emissions on the biomarkers of homemakers in rural areas of the Fenwei Plain, China |
title_full_unstemmed |
Effects of domestic solid fuel combustion emissions on the biomarkers of homemakers in rural areas of the Fenwei Plain, China |
title_sort |
effects of domestic solid fuel combustion emissions on the biomarkers of homemakers in rural areas of the fenwei plain, china |
publisher |
Elsevier |
series |
Ecotoxicology and Environmental Safety |
issn |
0147-6513 |
publishDate |
2021-05-01 |
description |
Background: The health effects of heavy solid fuel use in winter in rural China are of concern. The effects of air pollution resulting from domestic solid fuel combustion in rural households on rural homemakers’ biomarkers were revealed in this study. Methods: In total, 75 female homemakers from rural areas of Guanzhong Basin, the Fenwei Plain, People’s Republic of China, were randomly selected and divided into three groups (biomass users, coal users, and nonusers of solid fuel user [control group]). The differences in biological indicators, including 8-hydrox-2′-deoxyguanosine (8-OHdG), interlukin-6 (IL-6), and tumor necrosis factor-alpha (TNF-α) in urine samples as well as blood pressure (BP, including systolic BP [SBP] and diastolic BP [DBP]) and heart rate (HR) among the groups in winter and summer were investigated using statistical analysis. Results: IL-6, 8-OHdG, HR, SBP, and DBP were significantly higher in winter than in summer (P < 0.05) owing to the poor air quality resulted from the excessive use of solid fuels in winter. Significant seasonal differences in 8-OHdG were observed for both coal and biomass users. After the influence of confounders was removed, only IL-6 levels in the urine of solid fuel users were significantly higher than that of the control group. Conclusions: IL-6 is a sensitive biomarker representing inflammatory responses to particulate matter emitted through household solid fuel combustion. Locally, excessive use of solid fuels in winter posed serious PM2.5 pollution in this area and adverse effects on inflammatory biomarkers in these rural homemakers and induced DNA damage related to oxidative stress. |
topic |
Solid fuel combustion Biomarker Health effect Rural household Fenwei Plain |
url |
http://www.sciencedirect.com/science/article/pii/S0147651321002153 |
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