Surgical management of primary retroperitoneal tumors – Analysis of a single center experience
Background: Retroperitoneal tumors are a rare but diverse group of neoplasms that arise from the retroperitoneum. Local recurrence after surgical resection greatly influenced survival. We aimed to analyze factors affecting outcome after surgery at our institution. Materials and methods: A database w...
Main Authors: | , , , , , |
---|---|
Format: | Article |
Language: | English |
Published: |
Wolters Kluwer Medknow Publications
2017-06-01
|
Series: | Journal of Cancer Research and Practice |
Subjects: | |
Online Access: | http://www.sciencedirect.com/science/article/pii/S2311300616301951 |
id |
doaj-a5fc2bc2fd94461fb8bf766f12e70aa8 |
---|---|
record_format |
Article |
spelling |
doaj-a5fc2bc2fd94461fb8bf766f12e70aa82020-11-25T03:35:16ZengWolters Kluwer Medknow PublicationsJournal of Cancer Research and Practice2311-30062017-06-0142495210.1016/j.jcrpr.2017.01.001Surgical management of primary retroperitoneal tumors – Analysis of a single center experienceFang Lee0Tung-Sun Huang1Xin-Yi Ng2Wen-Chin Ko3Chien-Liang Liu4Jiunn-Chang Lin5Department of Surgery, Mackay Memorial Hospital and Mackay Medical College, Taipei, TaiwanDepartment of Surgery, Mackay Memorial Hospital and Mackay Medical College, Taipei, TaiwanDepartment of Surgery, Mackay Memorial Hospital and Mackay Medical College, Taipei, TaiwanDepartment of Surgery, Mackay Memorial Hospital and Mackay Medical College, Taipei, TaiwanDepartment of Surgery, Mackay Memorial Hospital and Mackay Medical College, Taipei, TaiwanDepartment of Surgery, Mackay Memorial Hospital and Mackay Medical College, Taipei, TaiwanBackground: Retroperitoneal tumors are a rare but diverse group of neoplasms that arise from the retroperitoneum. Local recurrence after surgical resection greatly influenced survival. We aimed to analyze factors affecting outcome after surgery at our institution. Materials and methods: A database was reviewed retrospectively to identify patients who underwent surgery for retroperitoneal tumors from 2007 to 2012. Patient demographics, operative outcomes and tumor variables were recorded. Multivariable analysis was performed to evaluate predictors for overall survival. Results: A total of 41 cases were treated surgically. The median diameter of tumors was 13.7 cm (2.5 cm–39 cm). In 90% of the cases, macroscopic complete resection was achieved. Twenty-one percent of these cases required en bloc multi-organ resection. Fifty percent developed local recurrence and 15% had distant metastasis during 7-years of follow up. Local recurrence was significantly associated with overall survival and macroscopic incomplete resection was a significant predictor of local recurrence. Conclusion: Complete resection of retroperitoneal tumors with oncologically free margins should be the goal at surgery. Microscopic complete resection plays an important role in improving survival.http://www.sciencedirect.com/science/article/pii/S2311300616301951Retroperitoneal tumor |
collection |
DOAJ |
language |
English |
format |
Article |
sources |
DOAJ |
author |
Fang Lee Tung-Sun Huang Xin-Yi Ng Wen-Chin Ko Chien-Liang Liu Jiunn-Chang Lin |
spellingShingle |
Fang Lee Tung-Sun Huang Xin-Yi Ng Wen-Chin Ko Chien-Liang Liu Jiunn-Chang Lin Surgical management of primary retroperitoneal tumors – Analysis of a single center experience Journal of Cancer Research and Practice Retroperitoneal tumor |
author_facet |
Fang Lee Tung-Sun Huang Xin-Yi Ng Wen-Chin Ko Chien-Liang Liu Jiunn-Chang Lin |
author_sort |
Fang Lee |
title |
Surgical management of primary retroperitoneal tumors – Analysis of a single center experience |
title_short |
Surgical management of primary retroperitoneal tumors – Analysis of a single center experience |
title_full |
Surgical management of primary retroperitoneal tumors – Analysis of a single center experience |
title_fullStr |
Surgical management of primary retroperitoneal tumors – Analysis of a single center experience |
title_full_unstemmed |
Surgical management of primary retroperitoneal tumors – Analysis of a single center experience |
title_sort |
surgical management of primary retroperitoneal tumors – analysis of a single center experience |
publisher |
Wolters Kluwer Medknow Publications |
series |
Journal of Cancer Research and Practice |
issn |
2311-3006 |
publishDate |
2017-06-01 |
description |
Background: Retroperitoneal tumors are a rare but diverse group of neoplasms that arise from the retroperitoneum. Local recurrence after surgical resection greatly influenced survival. We aimed to analyze factors affecting outcome after surgery at our institution.
Materials and methods: A database was reviewed retrospectively to identify patients who underwent surgery for retroperitoneal tumors from 2007 to 2012. Patient demographics, operative outcomes and tumor variables were recorded. Multivariable analysis was performed to evaluate predictors for overall survival.
Results: A total of 41 cases were treated surgically. The median diameter of tumors was 13.7 cm (2.5 cm–39 cm). In 90% of the cases, macroscopic complete resection was achieved. Twenty-one percent of these cases required en bloc multi-organ resection. Fifty percent developed local recurrence and 15% had distant metastasis during 7-years of follow up. Local recurrence was significantly associated with overall survival and macroscopic incomplete resection was a significant predictor of local recurrence.
Conclusion: Complete resection of retroperitoneal tumors with oncologically free margins should be the goal at surgery. Microscopic complete resection plays an important role in improving survival. |
topic |
Retroperitoneal tumor |
url |
http://www.sciencedirect.com/science/article/pii/S2311300616301951 |
work_keys_str_mv |
AT fanglee surgicalmanagementofprimaryretroperitonealtumorsanalysisofasinglecenterexperience AT tungsunhuang surgicalmanagementofprimaryretroperitonealtumorsanalysisofasinglecenterexperience AT xinying surgicalmanagementofprimaryretroperitonealtumorsanalysisofasinglecenterexperience AT wenchinko surgicalmanagementofprimaryretroperitonealtumorsanalysisofasinglecenterexperience AT chienliangliu surgicalmanagementofprimaryretroperitonealtumorsanalysisofasinglecenterexperience AT jiunnchanglin surgicalmanagementofprimaryretroperitonealtumorsanalysisofasinglecenterexperience |
_version_ |
1724555347695239168 |