Cholinergic modulation of dentate gyrus processing through dynamic reconfiguration of inhibitory circuits

Summary: The dentate gyrus (DG) of the hippocampus plays a key role in memory formation, and it is known to be modulated by septal projections. By performing electrophysiology and optogenetics, we evaluated the role of cholinergic modulation in the processing of afferent inputs in the DG. We show th...

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Bibliographic Details
Main Authors: Mora B. Ogando, Olivia Pedroncini, Noel Federman, Sebastián A. Romano, Luciano A. Brum, Guillermo M. Lanuza, Damian Refojo, Antonia Marin-Burgin
Format: Article
Language:English
Published: Elsevier 2021-08-01
Series:Cell Reports
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Online Access:http://www.sciencedirect.com/science/article/pii/S2211124721010068