Primary adrenal lymphoma as a cause of adrenal insufficiency, a report of two cases

Primary adrenal lymphoma (PAL) is a rare cause of adrenal insufficiency. More than 90% is of B-cell origin. The condition is bilateral in up to 75% of cases, with adrenal insufficiency in two of three patients. We report two cases of adrenal insufficiency presenting at the age of 70 and 79 years,...

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Main Authors:	Kaja Grønning, Archana Sharma, Maria Adele Mastroianni, Bo Daniel Karlsson, Eystein S Husebye, Kristian Løvås, Ingrid Nermoen
Format:	Article
Language:	English
Published:	Bioscientifica 2020-03-01
Series:	Endocrinology, Diabetes & Metabolism Case Reports
Online Access:	https://edm.bioscientifica.com/view/journals/edm/2020/1/EDM19-0131.xml

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spelling	doaj-a601422f66bf4a5f8a15f7c08021a0802020-11-25T02:51:31ZengBioscientificaEndocrinology, Diabetes & Metabolism Case Reports2052-05732052-05732020-03-01111510.1530/EDM-19-0131Primary adrenal lymphoma as a cause of adrenal insufficiency, a report of two casesKaja Grønning0Archana Sharma1Maria Adele Mastroianni2Bo Daniel Karlsson3Eystein S Husebye4Kristian Løvås5Ingrid Nermoen6Department of Endocrinology, Akershus University Hospital, Lorenskog, NorwayDepartment of Endocrinology, Akershus University Hospital, Lorenskog, NorwayDepartment of Haematology, Akershus University Hospital, Lorenskog, NorwayDepartment of Radiology, Akershus University Hospital, Lorenskog, NorwayDepartment of Clinical Science and K.G. Jebsen Center of Autoimmune Disorders, University of Bergen, Bergen, Norway; Department of Medicine, Haukeland University Hospital, Bergen, NorwayDepartment of Clinical Science and K.G. Jebsen Center of Autoimmune Disorders, University of Bergen, Bergen, Norway; Department of Medicine, Haukeland University Hospital, Bergen, NorwayDepartment of Endocrinology, Akershus University Hospital, Lorenskog, Norway; Institute of Clinical Medicine, Faculty of Medicine, University of Oslo, Oslo, Norway Primary adrenal lymphoma (PAL) is a rare cause of adrenal insufficiency. More than 90% is of B-cell origin. The condition is bilateral in up to 75% of cases, with adrenal insufficiency in two of three patients. We report two cases of adrenal insufficiency presenting at the age of 70 and 79 years, respectively. Both patients had negative 21-hydroxylase antibodies with bilateral adrenal lesions on CT. Biopsy showed B-cell lymphoma. One of the patients experienced intermittent disease regression on replacement dosage of glucocorticoids.https://edm.bioscientifica.com/view/journals/edm/2020/1/EDM19-0131.xml
collection	DOAJ
language	English
format	Article
sources	DOAJ
author	Kaja Grønning Archana Sharma Maria Adele Mastroianni Bo Daniel Karlsson Eystein S Husebye Kristian Løvås Ingrid Nermoen
spellingShingle	Kaja Grønning Archana Sharma Maria Adele Mastroianni Bo Daniel Karlsson Eystein S Husebye Kristian Løvås Ingrid Nermoen Primary adrenal lymphoma as a cause of adrenal insufficiency, a report of two cases Endocrinology, Diabetes & Metabolism Case Reports
author_facet	Kaja Grønning Archana Sharma Maria Adele Mastroianni Bo Daniel Karlsson Eystein S Husebye Kristian Løvås Ingrid Nermoen
author_sort	Kaja Grønning
title	Primary adrenal lymphoma as a cause of adrenal insufficiency, a report of two cases
title_short	Primary adrenal lymphoma as a cause of adrenal insufficiency, a report of two cases
title_full	Primary adrenal lymphoma as a cause of adrenal insufficiency, a report of two cases
title_fullStr	Primary adrenal lymphoma as a cause of adrenal insufficiency, a report of two cases
title_full_unstemmed	Primary adrenal lymphoma as a cause of adrenal insufficiency, a report of two cases
title_sort	primary adrenal lymphoma as a cause of adrenal insufficiency, a report of two cases
publisher	Bioscientifica
series	Endocrinology, Diabetes & Metabolism Case Reports
issn	2052-0573 2052-0573
publishDate	2020-03-01
description	Primary adrenal lymphoma (PAL) is a rare cause of adrenal insufficiency. More than 90% is of B-cell origin. The condition is bilateral in up to 75% of cases, with adrenal insufficiency in two of three patients. We report two cases of adrenal insufficiency presenting at the age of 70 and 79 years, respectively. Both patients had negative 21-hydroxylase antibodies with bilateral adrenal lesions on CT. Biopsy showed B-cell lymphoma. One of the patients experienced intermittent disease regression on replacement dosage of glucocorticoids.
url	https://edm.bioscientifica.com/view/journals/edm/2020/1/EDM19-0131.xml
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Primary adrenal lymphoma as a cause of adrenal insufficiency, a report of two cases

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