Ezrin regulating the cytoskeleton remodelling is required for hypoxia-induced Myofibroblast proliferation and migration

Ezrin regulating the cytoskeleton remodelling is required for hypoxia-induced Myofibroblast proliferation and migration

Background: Hypoxia pulmonary arterial hypertension (HPAH) is a disease of the small vessels characterized by sustained vasoconstriction, thickening of arterial walls, vascular remodelling, and progressive increase in pulmonary vascular resistance, thus leading to right heart failure and finally dea...

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Bibliographic Details
Main Authors: Bin eYi, Lin eChen, Jing eZeng, Jian eCui, Guansong eWang, Guisheng eQian, Karine eBelguise, xiaobo ewang, kaizhi eLu
Format: Article
Language:English
Published: Frontiers Media S.A. 2015-03-01
Series:Frontiers in Cardiovascular Medicine
Subjects:
pulmonary vascular remodelling
pulmonary artery smooth muscle-like cells
Pulmonary myofibroblast;
Hypoxia;
Ezrin;
Cell proliferation;
Online Access:http://journal.frontiersin.org/Journal/10.3389/fcvm.2015.00010/full

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