Regulation of Complement Activation by Heme Oxygenase-1 (HO-1) in Kidney Injury

Heme oxygenase is a cytoprotective enzyme with strong antioxidant and anti-apoptotic properties. Its cytoprotective role is mainly attributed to its enzymatic activity, which involves the degradation of heme to biliverdin with simultaneous release of carbon monoxide (CO). Recent studies uncovered a...

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Bibliographic Details
Main Authors: Maria G. Detsika, Elias A. Lianos
Format: Article
Language:English
Published: MDPI AG 2021-01-01
Series:Antioxidants
Subjects:
Online Access:https://www.mdpi.com/2076-3921/10/1/60