Regulation of Complement Activation by Heme Oxygenase-1 (HO-1) in Kidney Injury
Heme oxygenase is a cytoprotective enzyme with strong antioxidant and anti-apoptotic properties. Its cytoprotective role is mainly attributed to its enzymatic activity, which involves the degradation of heme to biliverdin with simultaneous release of carbon monoxide (CO). Recent studies uncovered a...
Main Authors: | Maria G. Detsika, Elias A. Lianos |
---|---|
Format: | Article |
Language: | English |
Published: |
MDPI AG
2021-01-01
|
Series: | Antioxidants |
Subjects: | |
Online Access: | https://www.mdpi.com/2076-3921/10/1/60 |
Similar Items
-
Heme Oxygenase 1: A Defensive Mediator in Kidney Diseases
by: Anne Grunenwald, et al.
Published: (2021-02-01) -
Relationship of Heme Oxygenase-1 (HO-1) Level with Onset and Severity in Normotensive Pregnancy and Severe Preeclampsia
by: John Johannes Wantania, et al.
Published: (2016-08-01) -
Presence of an HO-1 expression threshold in renal glomeruli
by: Maria G Detsika, et al.
Published: (2015-12-01) -
Heme Drives Susceptibility of Glomerular Endothelium to Complement Overactivation Due to Inefficient Upregulation of Heme Oxygenase-1
by: Olivia May, et al.
Published: (2018-12-01) -
Novel Heme Oxygenase-1 (HO-1) Inducers Based on Dimethyl Fumarate Structure
by: Valeria Sorrenti, et al.
Published: (2020-12-01)