Activation of Endothelial Cells by Antiphospholipid Antibodies—A Possible Mechanism Triggering Thrombosis in Patients with Antiphospholipid Syndrome

Activation of Endothelial Cells by Antiphospholipid Antibodies—A Possible Mechanism Triggering Thrombosis in Patients with Antiphospholipid Syndrome

Antiphospholipid syndrome (APS) is an antibody-mediated hypercoagulable state characterized by recurrent venous and arterial thromboembolic events. The presence of serum antibodies are collectively termed as antiphospholipid antibodies (aPL) and is the hallmark of the disease. Interest in the pathog...

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Bibliographic Details
Main Authors: Pei-Pei Chen, Yu-Chih Lin, Jeng-Hsien Yen, Tsan-Teng Ou, Chen-Ching Wu, Hong-Wen Liu, Wen-Chan Tsai
Format: Article
Language:English
Published: Wiley 2006-10-01
Series:Kaohsiung Journal of Medical Sciences
Subjects:
antiphospholipid antibodies
human umbilical vein endothelial cells
Online Access:http://www.sciencedirect.com/science/article/pii/S1607551X09703420

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