LXRs link metabolism to inflammation through Abca1-dependent regulation of membrane composition and TLR signaling
The liver X receptors (LXRs) are transcriptional regulators of lipid homeostasis that also have potent anti-inflammatory effects. The molecular basis for their anti-inflammatory effects is incompletely understood, but has been proposed to involve the indirect tethering of LXRs to inflammatory gene p...
Main Authors: | Ayaka Ito, Cynthia Hong, Xin Rong, Xuewei Zhu, Elizabeth J Tarling, Per Niklas Hedde, Enrico Gratton, John Parks, Peter Tontonoz |
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Format: | Article |
Language: | English |
Published: |
eLife Sciences Publications Ltd
2015-07-01
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Series: | eLife |
Subjects: | |
Online Access: | https://elifesciences.org/articles/08009 |
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