Eosinophilic Fasciitis Responds Well to Steroids and Methotrexate

Eosinophilic fasciitis (EF) is a rare systemic inflammatory disease with an unknown etiology. Making a diagnosis in such a case is always a challenge as it is a rare disease and mimics scleroderma and scleroderma-like syndrome but should be kept in mind as it carries a high mortality. Furthermore, i...

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Main Authors: Asmaa Sabr Mahdi1*, Iman H. Nasr2, Suad Al Jahdhami3, Atheel Kamona4 and, Humaid A. Al Wahshi
Format: Article
Language:English
Published: Oman Medical Specialty Board 2019-11-01
Series:Oman Medical Journal
Subjects:
Online Access:http://omjournal.org/articleDetails.aspx?coType=1&aId=2511
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spelling doaj-a66446c5c6464bce81320a68386b3f572020-11-24T22:00:06ZengOman Medical Specialty BoardOman Medical Journal1999-768X2070-52042019-11-0134656456710.5001/omj.2019.102Eosinophilic Fasciitis Responds Well to Steroids and MethotrexateAsmaa Sabr Mahdi1*,0 Iman H. Nasr2, 1Suad Al Jahdhami3, 2Atheel Kamona4 and 3Humaid A. Al Wahshi4Department of Medicine, Rheumatology Unit, Royal Hospital, Muscat, OmanImmunology Department, Royal Hospital, Muscat, OmanHistopathology Department, Sultan Qaboos University Hospital, Muscat, OmanRadiology Department, Royal Hospital, Muscat, OmanDepartment of Medicine, Rheumatology Unit, Royal Hospital, Muscat, OmanEosinophilic fasciitis (EF) is a rare systemic inflammatory disease with an unknown etiology. Making a diagnosis in such a case is always a challenge as it is a rare disease and mimics scleroderma and scleroderma-like syndrome but should be kept in mind as it carries a high mortality. Furthermore, it is a treatable disease. Here, we report a 41-year-old woman who presented to the rheumatology clinic at the Royal Hospital, Muscat, Oman, with a one-month history of bilateral swelling of the forearms along with skin tightness and fingers contraction. Her history and physical examination along with histopathological examination and magnetic resonance imaging findings were consistent with EF. She showed an excellent response to steroids and methotrexate which is not a combination therapy that has been tried or mentioned previously.http://omjournal.org/articleDetails.aspx?coType=1&aId=2511eosinophilic fasciitisfasciitiseosinophilsforearm
collection DOAJ
language English
format Article
sources DOAJ
author Asmaa Sabr Mahdi1*,
Iman H. Nasr2,
Suad Al Jahdhami3,
Atheel Kamona4 and
Humaid A. Al Wahshi
spellingShingle Asmaa Sabr Mahdi1*,
Iman H. Nasr2,
Suad Al Jahdhami3,
Atheel Kamona4 and
Humaid A. Al Wahshi
Eosinophilic Fasciitis Responds Well to Steroids and Methotrexate
Oman Medical Journal
eosinophilic fasciitis
fasciitis
eosinophils
forearm
author_facet Asmaa Sabr Mahdi1*,
Iman H. Nasr2,
Suad Al Jahdhami3,
Atheel Kamona4 and
Humaid A. Al Wahshi
author_sort Asmaa Sabr Mahdi1*,
title Eosinophilic Fasciitis Responds Well to Steroids and Methotrexate
title_short Eosinophilic Fasciitis Responds Well to Steroids and Methotrexate
title_full Eosinophilic Fasciitis Responds Well to Steroids and Methotrexate
title_fullStr Eosinophilic Fasciitis Responds Well to Steroids and Methotrexate
title_full_unstemmed Eosinophilic Fasciitis Responds Well to Steroids and Methotrexate
title_sort eosinophilic fasciitis responds well to steroids and methotrexate
publisher Oman Medical Specialty Board
series Oman Medical Journal
issn 1999-768X
2070-5204
publishDate 2019-11-01
description Eosinophilic fasciitis (EF) is a rare systemic inflammatory disease with an unknown etiology. Making a diagnosis in such a case is always a challenge as it is a rare disease and mimics scleroderma and scleroderma-like syndrome but should be kept in mind as it carries a high mortality. Furthermore, it is a treatable disease. Here, we report a 41-year-old woman who presented to the rheumatology clinic at the Royal Hospital, Muscat, Oman, with a one-month history of bilateral swelling of the forearms along with skin tightness and fingers contraction. Her history and physical examination along with histopathological examination and magnetic resonance imaging findings were consistent with EF. She showed an excellent response to steroids and methotrexate which is not a combination therapy that has been tried or mentioned previously.
topic eosinophilic fasciitis
fasciitis
eosinophils
forearm
url http://omjournal.org/articleDetails.aspx?coType=1&aId=2511
work_keys_str_mv AT asmaasabrmahdi1 eosinophilicfasciitisrespondswelltosteroidsandmethotrexate
AT imanhnasr2 eosinophilicfasciitisrespondswelltosteroidsandmethotrexate
AT suadaljahdhami3 eosinophilicfasciitisrespondswelltosteroidsandmethotrexate
AT atheelkamona4and eosinophilicfasciitisrespondswelltosteroidsandmethotrexate
AT humaidaalwahshi eosinophilicfasciitisrespondswelltosteroidsandmethotrexate
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