Cytoprotection against Hypoxic and/or MPP+ Injury: Effect of δ–Opioid Receptor Activation on Caspase 3

Cytoprotection against Hypoxic and/or MPP+ Injury: Effect of δ–Opioid Receptor Activation on Caspase 3

The pathological changes of Parkinson’s disease (PD) are, at least partially, associated with the dysregulation of PTEN-induced putative kinase 1 (PINK1) and caspase 3. Since hypoxic and neurotoxic insults are underlying causes of PD, and since δ-opioid receptor (DOR) is neuroprotective against hypo...

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Bibliographic Details
Main Authors: Yuan Xu, Feng Zhi, Naiyuan Shao, Rong Wang, Yilin Yang, Ying Xia
Format: Article
Language:English
Published: MDPI AG 2016-08-01
Series:International Journal of Molecular Sciences
Subjects:
Parkinson’s disease
δ-opioid receptor
cytoprotection
hypoxia
MPP+
PINK1
caspase 3
Online Access:http://www.mdpi.com/1422-0067/17/8/1179

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