Thrombospondin-1/CD47 Interaction Regulates Th17 and Treg Differentiation in Psoriasis

Thrombospondin-1/CD47 Interaction Regulates Th17 and Treg Differentiation in Psoriasis

Accumulating evidence on the role of Thrombospondin-1 (TSP-1) in the immune response has emerged during the last years. In spite of the importance of TSP-1 not only as anti-angiogenic factor but also as an immunomodulatory molecule, studies on the role of TSP-1 in psoriasis have been neglected. TSP-...

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Bibliographic Details
Main Authors: Pedro Rodríguez-Jiménez, Pablo Chicharro, Mar Llamas-Velasco, Danay Cibrian, Laura Trigo-Torres, Alicia Vara, María Jiménez-Fernández, Javier Sevilla-Montero, Maria J. Calzada, Francisco Sánchez-Madrid, Hortensia de la Fuente, Esteban Daudén
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-06-01
Series:Frontiers in Immunology
Subjects:
psoriasis
CD47
TSP-1
Th17
Treg cells
Online Access:https://www.frontiersin.org/article/10.3389/fimmu.2019.01268/full

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