The serine protease inhibitor serpinE2 is a novel target of ERK signaling involved in human colorectal tumorigenesis

The serine protease inhibitor serpinE2 is a novel target of ERK signaling involved in human colorectal tumorigenesis

<p>Abstract</p> <p>Background</p> <p>Among the most harmful of all genetic abnormalities that appear in colorectal cancer (CRC) development are mutations of KRAS and its downstream effector BRAF as they result in abnormal extracellular signal-related kinase (ERK) signal...

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Bibliographic Details
Main Authors: Boucher Marie-Josée, Lussier Jacques G, Carrier Julie C, Cagnol Sébastien, Durand Véronique, Lemieux Etienne, Bergeron Sébastien, Rivard Nathalie
Format: Article
Language:English
Published: BMC 2010-10-01
Series:Molecular Cancer
Online Access:http://www.molecular-cancer.com/content/9/1/271

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