The Role of Sirtuin-1 in Immune Response and Systemic Lupus Erythematosus

The Role of Sirtuin-1 in Immune Response and Systemic Lupus Erythematosus

Systemic lupus erythematosus (SLE) is a potentially fatal multisystem inflammatory chronic disorder, the etiology and pathogenesis of which remain unclear. The loss of immune tolerance in SLE patients contributes to the production of autoantibodies that attack multiple organs and tissues, such as th...

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Bibliographic Details
Main Authors:	Yueqi Qiu, Xingyu Zhou, Yu Liu, Siqi Tan, Yaping Li
Format:	Article
Language:	English
Published:	Frontiers Media S.A. 2021-04-01
Series:	Frontiers in Immunology
Subjects:	systemic lupus erythematosus Sirtuin-1 pathogenesis immune cells epigenetics histone deacetylase
Online Access:	https://www.frontiersin.org/articles/10.3389/fimmu.2021.632383/full

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