Pan cytokeratin expression by meningiomas of the brain
Meningiomas of the brain are the second most common tumor of the CNS in adults, accounting about 30% of all primary tumors. Aim. In order to determine the presence and to assess the expression level of cytokeratin (CK) in benign and malignant brain meningiomas tissue samples were obtained during...
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Zaporozhye State Medical University
2015-04-01
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| Series: | Patologìâ |
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| Online Access: | http://pat.zsmu.edu.ua/article/view/42828/39225 |
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doaj-a6cdacc653d7463e98de1ca16101983a2020-11-24T22:46:36ZengZaporozhye State Medical UniversityPatologìâ2306-80272310-12372015-04-011313410.14739/2310-1237.2015.1.42828Pan cytokeratin expression by meningiomas of the brainS. I. Tertishniy W. E. VotevaMeningiomas of the brain are the second most common tumor of the CNS in adults, accounting about 30% of all primary tumors. Aim. In order to determine the presence and to assess the expression level of cytokeratin (CK) in benign and malignant brain meningiomas tissue samples were obtained during neurosurgical operations from 30 patients. Methods and results. Tissue samples were studied immunohistochemically by using monoclonal antibodies Mo a-Hu Cytokeratine (PanCK), Clone AE1/AE3 («DAKO», Denmark). It was established that anaplastic meningiomas expressed CK in 80% of cases. Among benign meningiomas positive expression was found in 40% of fibroblastic subtypes. http://pat.zsmu.edu.ua/article/view/42828/39225MeningiomaHistogenesisCytokeratin |
| collection |
DOAJ |
| language |
English |
| format |
Article |
| sources |
DOAJ |
| author |
S. I. Tertishniy W. E. Voteva |
| spellingShingle |
S. I. Tertishniy W. E. Voteva Pan cytokeratin expression by meningiomas of the brain Patologìâ Meningioma Histogenesis Cytokeratin |
| author_facet |
S. I. Tertishniy W. E. Voteva |
| author_sort |
S. I. Tertishniy |
| title |
Pan cytokeratin expression by meningiomas of the brain |
| title_short |
Pan cytokeratin expression by meningiomas of the brain |
| title_full |
Pan cytokeratin expression by meningiomas of the brain |
| title_fullStr |
Pan cytokeratin expression by meningiomas of the brain |
| title_full_unstemmed |
Pan cytokeratin expression by meningiomas of the brain |
| title_sort |
pan cytokeratin expression by meningiomas of the brain |
| publisher |
Zaporozhye State Medical University |
| series |
Patologìâ |
| issn |
2306-8027 2310-1237 |
| publishDate |
2015-04-01 |
| description |
Meningiomas of the brain are the second most common tumor of the CNS in adults, accounting about 30% of all primary tumors.
Aim. In order to determine the presence and to assess the expression level of cytokeratin (CK) in benign and malignant brain meningiomas tissue samples were obtained during neurosurgical operations from 30 patients.
Methods and results. Tissue samples were studied immunohistochemically by using monoclonal antibodies Mo a-Hu Cytokeratine (PanCK), Clone AE1/AE3 («DAKO», Denmark). It was established that anaplastic meningiomas expressed CK in 80% of cases. Among benign meningiomas positive expression was found in 40% of fibroblastic subtypes.
|
| topic |
Meningioma Histogenesis Cytokeratin |
| url |
http://pat.zsmu.edu.ua/article/view/42828/39225 |
| work_keys_str_mv |
AT sitertishniy pancytokeratinexpressionbymeningiomasofthebrain AT wevoteva pancytokeratinexpressionbymeningiomasofthebrain |
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1725684643324231680 |