The comparison of estrogen metabolites between active and inactive postmenopausal women
Introduction: Regular physical activity may alter estrogen metabolism. The aim of the present study was to compare estrogen metabolites between active and inactive postmenopausal women. Materials and Methods: 75 postmenopausal women were asked to fill in the Beck questionnaire. Based on the que...
| Main Authors: | , , , |
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| Format: | Article |
| Language: | fas |
| Published: |
Jahrom University of Medical Sciences
2013-07-01
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| Series: | فصلنامه دانشگاه علوم پزشکی جهرم |
| Subjects: | |
| Online Access: | http://jmj.jums.ac.ir/browse.php?a_id=190&slc_lang=en&sid=1&ftxt=1 |
| Summary: | Introduction:
Regular physical activity may alter estrogen metabolism. The aim of the present study was to compare estrogen metabolites between active and inactive postmenopausal women.
Materials and Methods:
75 postmenopausal women were asked to fill in the Beck questionnaire. Based on the questionnaire scales, they were divided into two groups: active and inactive. Blood samples were taken in fasting state from all subjects and serum concentration of 2-hydroxyestron and 16-hydroxyestron metabolites and their ratios measured. Independent t-test was used for data analysis.
Results:
The results showed that 2-hydroxyestron metabolite level and 2-hydroxyestron/16-hydroxyestron ratio were significantly higher among active postmenopausal women than inactive postmenopausal women but 16-hydroxyestron metabolite level was significantly lower among active postmenopausal women than inactive postmenopausal women.
Conclusion:
It is concluded that long-term physical activity can reduce breast cancer risk in postmenopausal women through influencing the estrogen metabolites.
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| ISSN: | 2008-7993 2008-8442 |