Predicting 1-year mortality after hospitalization for community-acquired pneumonia.
Community-acquired pneumonia (CAP) is a major public health problem with high short- and long-term mortality. The main aim of this study was to develop and validate a specific prognostic index for one-year mortality in patients admitted for CAP.This was an observational, prospective study of adults...
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doaj-a6f5486d9ff84f6a85e56be47f88ce4a2020-11-25T02:12:00ZengPublic Library of Science (PLoS)PLoS ONE1932-62032018-01-01132e019275010.1371/journal.pone.0192750Predicting 1-year mortality after hospitalization for community-acquired pneumonia.Ane UrangaJose M QuintanaUrko AguirreAmaia ArtarazRosa DiezSilvia PascualAitor BallazPedro P EspañaCommunity-acquired pneumonia (CAP) is a major public health problem with high short- and long-term mortality. The main aim of this study was to develop and validate a specific prognostic index for one-year mortality in patients admitted for CAP.This was an observational, prospective study of adults aged ≥18 years admitted to Galdakao-Usansolo Hospital (Bizkaia, Spain) from January 2001 to July 2009 with a diagnosis of CAP surviving the first 15 days. The entire cohort was divided into two parts, in order to develop a one-year mortality predictive model in the derivation cohort, before validation using the second cohort.A total of 2351 patients were included and divided into a derivation and a validation cohort. After deaths within 15 days were excluded, one-year mortality was 10.63%. A predictive model was created in order to predict one-year mortality, with a weighted score that included: aged over 80 years (4 points), congestive heart failure (2 points), dementia (6 points), respiratory rate ≥30 breaths per minute (2 points) and blood urea nitrogen >30 mg/dL (3 points) as predictors of higher risk with C-index of 0.76. This new model showed better predictive ability than current risk scores, PSI, CURB65 and SCAP with C-index of 0.73, 0.69 and 0.70, respectively.An easy-to-use score, called the one-year CAPSI, may be useful for identifying patients with a high probability of dying after an episode of CAP.http://europepmc.org/articles/PMC5812619?pdf=render |
collection |
DOAJ |
language |
English |
format |
Article |
sources |
DOAJ |
author |
Ane Uranga Jose M Quintana Urko Aguirre Amaia Artaraz Rosa Diez Silvia Pascual Aitor Ballaz Pedro P España |
spellingShingle |
Ane Uranga Jose M Quintana Urko Aguirre Amaia Artaraz Rosa Diez Silvia Pascual Aitor Ballaz Pedro P España Predicting 1-year mortality after hospitalization for community-acquired pneumonia. PLoS ONE |
author_facet |
Ane Uranga Jose M Quintana Urko Aguirre Amaia Artaraz Rosa Diez Silvia Pascual Aitor Ballaz Pedro P España |
author_sort |
Ane Uranga |
title |
Predicting 1-year mortality after hospitalization for community-acquired pneumonia. |
title_short |
Predicting 1-year mortality after hospitalization for community-acquired pneumonia. |
title_full |
Predicting 1-year mortality after hospitalization for community-acquired pneumonia. |
title_fullStr |
Predicting 1-year mortality after hospitalization for community-acquired pneumonia. |
title_full_unstemmed |
Predicting 1-year mortality after hospitalization for community-acquired pneumonia. |
title_sort |
predicting 1-year mortality after hospitalization for community-acquired pneumonia. |
publisher |
Public Library of Science (PLoS) |
series |
PLoS ONE |
issn |
1932-6203 |
publishDate |
2018-01-01 |
description |
Community-acquired pneumonia (CAP) is a major public health problem with high short- and long-term mortality. The main aim of this study was to develop and validate a specific prognostic index for one-year mortality in patients admitted for CAP.This was an observational, prospective study of adults aged ≥18 years admitted to Galdakao-Usansolo Hospital (Bizkaia, Spain) from January 2001 to July 2009 with a diagnosis of CAP surviving the first 15 days. The entire cohort was divided into two parts, in order to develop a one-year mortality predictive model in the derivation cohort, before validation using the second cohort.A total of 2351 patients were included and divided into a derivation and a validation cohort. After deaths within 15 days were excluded, one-year mortality was 10.63%. A predictive model was created in order to predict one-year mortality, with a weighted score that included: aged over 80 years (4 points), congestive heart failure (2 points), dementia (6 points), respiratory rate ≥30 breaths per minute (2 points) and blood urea nitrogen >30 mg/dL (3 points) as predictors of higher risk with C-index of 0.76. This new model showed better predictive ability than current risk scores, PSI, CURB65 and SCAP with C-index of 0.73, 0.69 and 0.70, respectively.An easy-to-use score, called the one-year CAPSI, may be useful for identifying patients with a high probability of dying after an episode of CAP. |
url |
http://europepmc.org/articles/PMC5812619?pdf=render |
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