Pharmacologic Prophylaxis and Treatment of Venous Thromboembolism after Knee Arthroplasty
The objective of this study was to evaluate the efficacy of unfractionated heparin, warfarin and low molecular weight heparins (LMWH) used for the prevention of venous thromboembolism in arthroplastic surgery of the knee joint. Methods: In this prospective study from August 2002 to November 2004, 60...
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doaj-a6fe23444fcb4ad2900bf8c40f7adc2e2020-11-25T02:55:14ZengSultan Qaboos UniversitySultan Qaboos University Medical Journal 2075-051X2075-05282007-04-017147501205Pharmacologic Prophylaxis and Treatment of Venous Thromboembolism after Knee ArthroplastyJamal S Shawabkeh0Malek M Ghnaimat1Ammar M Hijazi2Orthopedic Department, Royal Jordanian Medical Services, P O Box 517, Amman 11118, JordanOrthopedic Department, Royal Jordanian Medical Services, P O Box 517, Amman 11118, JordanOrthopedic Department, Royal Jordanian Medical Services, P O Box 517, Amman 11118, JordanThe objective of this study was to evaluate the efficacy of unfractionated heparin, warfarin and low molecular weight heparins (LMWH) used for the prevention of venous thromboembolism in arthroplastic surgery of the knee joint. Methods: In this prospective study from August 2002 to November 2004, 60 patients were included and divided into three groups with equal numbers, with each group receiving different treatment protocol. Postoperatively, the occurrence of symptomatic deep vein thrombosis (DVT) or pulmonary embolism (PE) was recorded during the first 30 days after surgery and at a routine follow-up visit. Results: A significantly lower prevalence of DVT and PE was found in patients using warfarin and LMWH as prophylaxis in comparison with patients using unfractionated heparin. Conclusion: Warfarin and low molecular weight heparins are more beneficial and effective than unfractionated heparin for DVT and PE prophylaxis in arthroplastic knee surgeries.https://journals.squ.edu.om/index.php/squmj/article/view/1277arthroplasty, deep vein thrombosis (dvt), prophylaxis, low molecular weight heparin, warfarin. |
collection |
DOAJ |
language |
English |
format |
Article |
sources |
DOAJ |
author |
Jamal S Shawabkeh Malek M Ghnaimat Ammar M Hijazi |
spellingShingle |
Jamal S Shawabkeh Malek M Ghnaimat Ammar M Hijazi Pharmacologic Prophylaxis and Treatment of Venous Thromboembolism after Knee Arthroplasty Sultan Qaboos University Medical Journal arthroplasty, deep vein thrombosis (dvt), prophylaxis, low molecular weight heparin, warfarin. |
author_facet |
Jamal S Shawabkeh Malek M Ghnaimat Ammar M Hijazi |
author_sort |
Jamal S Shawabkeh |
title |
Pharmacologic Prophylaxis and Treatment of Venous Thromboembolism after Knee Arthroplasty |
title_short |
Pharmacologic Prophylaxis and Treatment of Venous Thromboembolism after Knee Arthroplasty |
title_full |
Pharmacologic Prophylaxis and Treatment of Venous Thromboembolism after Knee Arthroplasty |
title_fullStr |
Pharmacologic Prophylaxis and Treatment of Venous Thromboembolism after Knee Arthroplasty |
title_full_unstemmed |
Pharmacologic Prophylaxis and Treatment of Venous Thromboembolism after Knee Arthroplasty |
title_sort |
pharmacologic prophylaxis and treatment of venous thromboembolism after knee arthroplasty |
publisher |
Sultan Qaboos University |
series |
Sultan Qaboos University Medical Journal |
issn |
2075-051X 2075-0528 |
publishDate |
2007-04-01 |
description |
The objective of this study was to evaluate the efficacy of unfractionated heparin, warfarin and low molecular weight heparins (LMWH) used for the prevention of venous thromboembolism in arthroplastic surgery of the knee joint. Methods: In this prospective study from August 2002 to November 2004, 60 patients were included and divided into three groups with equal numbers, with each group receiving different treatment protocol. Postoperatively, the occurrence of symptomatic deep vein thrombosis (DVT) or pulmonary embolism (PE) was recorded during the first 30 days after surgery and at a routine follow-up visit. Results: A significantly lower prevalence of DVT and PE was found in patients using warfarin and LMWH as prophylaxis in comparison with patients using unfractionated heparin. Conclusion: Warfarin and low molecular weight heparins are more beneficial and effective than unfractionated heparin for DVT and PE prophylaxis in arthroplastic knee surgeries. |
topic |
arthroplasty, deep vein thrombosis (dvt), prophylaxis, low molecular weight heparin, warfarin. |
url |
https://journals.squ.edu.om/index.php/squmj/article/view/1277 |
work_keys_str_mv |
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