Prophylactic and therapeutic efficacy of avian antibodies against influenza virus H5N1 and H1N1 in mice.

BACKGROUND: Pandemic influenza poses a serious threat to global health and the world economy. While vaccines are currently under development, passive immunization could offer an alternative strategy to prevent and treat influenza virus infection. Attempts to develop monoclonal antibodies (mAbs) have...

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Bibliographic Details
Main Authors: Huan H Nguyen, Terrence M Tumpey, Hae-Jung Park, Young-Ho Byun, Linh D Tran, Van D Nguyen, Paul E Kilgore, Cecil Czerkinsky, Jacqueline M Katz, Baik Lin Seong, Jae Min Song, Young Bong Kim, Hoa T Do, Tung Nguyen, Cam V Nguyen
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2010-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC2854139?pdf=render