The Protective Role of Mitochondrial Ferritin on Erastin-Induced Ferroptosis
Ferroptosis, a newly identified form of regulated cell death, is characterized by overwhelming iron-dependent accumulation of lethal lipid reactive oxygen species (ROS). Preventing cellular iron overload by reducing iron uptake and increasing iron storage may contribute to inhibit ferroptosis. Mitoc...
Main Authors: | Yue-Qi Wang, Shi-Yang Chang, Qiong Wu, Yu-jing Gou, Linpei Jia, Cui Yan-Mei, Peng Yu, Zhen-Hua Shi, Wen-Shuang Wu, Guofen Gao, Yan-Zhong Chang |
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Format: | Article |
Language: | English |
Published: |
Frontiers Media S.A.
2016-12-01
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Series: | Frontiers in Aging Neuroscience |
Subjects: | |
Online Access: | http://journal.frontiersin.org/Journal/10.3389/fnagi.2016.00308/full |
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