CD11c+ B Cells Are Mainly Memory Cells, Precursors of Antibody Secreting Cells in Healthy Donors

CD11c+ B Cells Are Mainly Memory Cells, Precursors of Antibody Secreting Cells in Healthy Donors

CD11c+ B cells have been reported to be increased in autoimmune diseases, but they are detected in the blood of healthy individuals as well. We aimed to characterize CD11c+ B cells from healthy donors by flow cytometry, microarray analysis, and in vitro functional assays. Here, we report that CD11c+...

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Bibliographic Details
Main Authors: Marie-Laure Golinski, Mélanie Demeules, Céline Derambure, Gaetan Riou, Maud Maho-Vaillant, Olivier Boyer, Pascal Joly, Sébastien Calbo
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-02-01
Series:Frontiers in Immunology
Subjects:
human
CD11c
B cells
microarray
plasma cells
pemphigus
Online Access:https://www.frontiersin.org/article/10.3389/fimmu.2020.00032/full

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