Evidence-Based View of Safety and Effectiveness of Prokineticin Receptors Antagonists during Pregnancy

Evidence-Based View of Safety and Effectiveness of Prokineticin Receptors Antagonists during Pregnancy

Endocrine gland derived vascular endothelial growth factor (EG-VEGF) is a canonical member of the prokineticin (PROKs) family. It acts via the two G-protein coupled receptors, namely PROKR1 and PROKR2. We have recently demonstrated that EG-VEGF is highly expressed in the human placenta; contributes...

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Bibliographic Details
Main Authors: Deborah Reynaud, Frederic Sergent, Roland Abi Nahed, Wael Traboulsi, Constance Collet, Christel Marquette, Pascale Hoffmann, Gianfranco Balboni, Qun-Yong Zhou, Padma Murthi, Mohamed Benharouga, Nadia Alfaidy
Format: Article
Language:English
Published: MDPI AG 2021-03-01
Series:Biomedicines
Subjects:
prokineticin antagonists
EG-VEGF
pregnancy pathologies
therapy
angiogenesis
trophoblast invasion
Online Access:https://www.mdpi.com/2227-9059/9/3/309

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