Comparison of Salivary Beta Glucuronidase Activity in Chronic Periodontitis Patients with and without Diabetes Mellitus
Aim of the study: The aim of the study was to estimate the salivary beta glucuronidase (β) activity in patients with chronic periodontitis with and without diabetes mellitus and to evaluate the relationship between Beta Glucuronidase activity and Periodontal clinical parameters. Materials and M...
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doaj-a74062a886964a24b40659703965962d2020-11-25T03:39:14ZengJCDR Research and Publications Private LimitedJournal of Clinical and Diagnostic Research2249-782X0973-709X2014-06-0186ZC19ZC2110.7860/JCDR/2014/8713.4476Comparison of Salivary Beta Glucuronidase Activity in Chronic Periodontitis Patients with and without Diabetes MellitusJaiganesh Ramamurthy0Jayakumar ND1Sheeja Varghese2Reader, Department of Periodontics, Saveetha Dental College, Chennai, Tamilnadu, India.Professor and Head, Department of Periodontics, Saveetha Dental College, Chennai, Tamilnadu, India.Professor, Department of Periodontics, Saveetha Dental College, Chennai, Tamilnadu, India.Aim of the study: The aim of the study was to estimate the salivary beta glucuronidase (β) activity in patients with chronic periodontitis with and without diabetes mellitus and to evaluate the relationship between Beta Glucuronidase activity and Periodontal clinical parameters. Materials and Methods: The study consisted of 80 patients of both sexes with age ranging from 20-60 years and they were divided into four groups. Clinical parameters such as Gingival index, Probing depth and Clinical attachment loss were measured. Salivary Beta Glucuronidase activity was measured using spectrophotometer with reagents like phenolphthalein glucuronic acid, phosphate and glycine buffer. Results: The mean BG activity of Group IV (1.17 ± 0.27) was significantly higher than mean BGA levels of Group I, II, III. The p-value was < 0.05. The mean BGA levels of Group III (0.78 ± 0.17) was significantly higher than mean BGA levels of Group I, Group II at 5 % level. There was a significant positive linear relationship between salivary β Glucuronidase level and Probing Depth, clinical attachment level in the experimental Groups. Conclusion: The salivary β Glucuronidase level was higher in Diabetic patients with periodontitis than nondiabetic periodontitis patients.https://jcdr.net/articles/PDF/4476/8713_CE(Ra1)_F(H)_PF1(PAK)_PFA(AK)_PF2(AGAK)_PF2(PN).pdfbeta glucuronidasediabetes mellitusperiodontitissaliva |
collection |
DOAJ |
language |
English |
format |
Article |
sources |
DOAJ |
author |
Jaiganesh Ramamurthy Jayakumar ND Sheeja Varghese |
spellingShingle |
Jaiganesh Ramamurthy Jayakumar ND Sheeja Varghese Comparison of Salivary Beta Glucuronidase Activity in Chronic Periodontitis Patients with and without Diabetes Mellitus Journal of Clinical and Diagnostic Research beta glucuronidase diabetes mellitus periodontitis saliva |
author_facet |
Jaiganesh Ramamurthy Jayakumar ND Sheeja Varghese |
author_sort |
Jaiganesh Ramamurthy |
title |
Comparison of Salivary Beta Glucuronidase Activity in Chronic Periodontitis Patients with and without Diabetes Mellitus |
title_short |
Comparison of Salivary Beta Glucuronidase Activity in Chronic Periodontitis Patients with and without Diabetes Mellitus |
title_full |
Comparison of Salivary Beta Glucuronidase Activity in Chronic Periodontitis Patients with and without Diabetes Mellitus |
title_fullStr |
Comparison of Salivary Beta Glucuronidase Activity in Chronic Periodontitis Patients with and without Diabetes Mellitus |
title_full_unstemmed |
Comparison of Salivary Beta Glucuronidase Activity in Chronic Periodontitis Patients with and without Diabetes Mellitus |
title_sort |
comparison of salivary beta glucuronidase activity in chronic periodontitis patients with and without diabetes mellitus |
publisher |
JCDR Research and Publications Private Limited |
series |
Journal of Clinical and Diagnostic Research |
issn |
2249-782X 0973-709X |
publishDate |
2014-06-01 |
description |
Aim of the study: The aim of the study was to estimate the
salivary beta glucuronidase (β) activity in patients with chronic
periodontitis with and without diabetes mellitus and to evaluate
the relationship between Beta Glucuronidase activity and
Periodontal clinical parameters.
Materials and Methods: The study consisted of 80 patients
of both sexes with age ranging from 20-60 years and they
were divided into four groups. Clinical parameters such as
Gingival index, Probing depth and Clinical attachment loss were
measured. Salivary Beta Glucuronidase activity was measured
using spectrophotometer with reagents like phenolphthalein
glucuronic acid, phosphate and glycine buffer.
Results: The mean BG activity of Group IV (1.17 ± 0.27) was
significantly higher than mean BGA levels of Group I, II, III. The
p-value was < 0.05. The mean BGA levels of Group III (0.78 ±
0.17) was significantly higher than mean BGA levels of Group
I, Group II at 5 % level. There was a significant positive linear
relationship between salivary β Glucuronidase level and Probing
Depth, clinical attachment level in the experimental Groups.
Conclusion: The salivary β Glucuronidase level was higher
in Diabetic patients with periodontitis than nondiabetic
periodontitis patients. |
topic |
beta glucuronidase diabetes mellitus periodontitis saliva |
url |
https://jcdr.net/articles/PDF/4476/8713_CE(Ra1)_F(H)_PF1(PAK)_PFA(AK)_PF2(AGAK)_PF2(PN).pdf |
work_keys_str_mv |
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