Post-Coital Antifertility Activity of Hibiscus rosa-sinensis Linn. Roots

Post-Coital Antifertility Activity of Hibiscus rosa-sinensis Linn. Roots

Ancient literature mentions the use of a number of plants/preparations for fertility regulation. Some local contraceptive agents have also been described in Ayurvedic and Unani texts. Documented experiments or clinical data are, however, lacking. Therefore, the present study was undertaken to explor...

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Main Authors: Neeru Vasudeva, S. K. Sharma
Format: Article
Language:English
Published: Hindawi Limited 2008-01-01
Series:Evidence-Based Complementary and Alternative Medicine
Online Access:http://dx.doi.org/10.1093/ecam/nem003
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spelling doaj-a747b38fd03d4afd836dcd205a1deb7b2020-11-24T22:41:23ZengHindawi LimitedEvidence-Based Complementary and Alternative Medicine1741-427X1741-42882008-01-0151919410.1093/ecam/nem003Post-Coital Antifertility Activity of Hibiscus rosa-sinensis Linn. RootsNeeru Vasudeva0S. K. Sharma1Pharmacognosy and Phytochemistry Division, Faculty of Pharmaceutical Sciences, Guru Jambheshwar University of Science and Technology, Hisar 125001, IndiaPharmacognosy and Phytochemistry Division, Faculty of Pharmaceutical Sciences, Guru Jambheshwar University of Science and Technology, Hisar 125001, IndiaAncient literature mentions the use of a number of plants/preparations for fertility regulation. Some local contraceptive agents have also been described in Ayurvedic and Unani texts. Documented experiments or clinical data are, however, lacking. Therefore, the present study was undertaken to explore the antifertility and estrogenic activity of ethanolic extract of the roots of Hibiscus rosa-sinensis Linn. A strong anti-implantation (inhibition 100%) and uterotropic activity was observed at the dose level of 400 mg/kg body weight. Histological studies were carried out to confirm this effect.http://dx.doi.org/10.1093/ecam/nem003
collection DOAJ
language English
format Article
sources DOAJ
author Neeru Vasudeva
S. K. Sharma
spellingShingle Neeru Vasudeva
S. K. Sharma
Post-Coital Antifertility Activity of Hibiscus rosa-sinensis Linn. Roots
Evidence-Based Complementary and Alternative Medicine
author_facet Neeru Vasudeva
S. K. Sharma
author_sort Neeru Vasudeva
title Post-Coital Antifertility Activity of Hibiscus rosa-sinensis Linn. Roots
title_short Post-Coital Antifertility Activity of Hibiscus rosa-sinensis Linn. Roots
title_full Post-Coital Antifertility Activity of Hibiscus rosa-sinensis Linn. Roots
title_fullStr Post-Coital Antifertility Activity of Hibiscus rosa-sinensis Linn. Roots
title_full_unstemmed Post-Coital Antifertility Activity of Hibiscus rosa-sinensis Linn. Roots
title_sort post-coital antifertility activity of hibiscus rosa-sinensis linn. roots
publisher Hindawi Limited
series Evidence-Based Complementary and Alternative Medicine
issn 1741-427X
1741-4288
publishDate 2008-01-01
description Ancient literature mentions the use of a number of plants/preparations for fertility regulation. Some local contraceptive agents have also been described in Ayurvedic and Unani texts. Documented experiments or clinical data are, however, lacking. Therefore, the present study was undertaken to explore the antifertility and estrogenic activity of ethanolic extract of the roots of Hibiscus rosa-sinensis Linn. A strong anti-implantation (inhibition 100%) and uterotropic activity was observed at the dose level of 400 mg/kg body weight. Histological studies were carried out to confirm this effect.
url http://dx.doi.org/10.1093/ecam/nem003
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