Efficacy of Misoprostol versus Syntometrine in the Prevention of Postpartum Hemorrhage

effects of oral misoprostol versus syntometrine for prevention of primary postpartum hemorrhage. Methods: Interventional study; Eighty patients were divided into two equal groups. Misoprostol 600 microgram single dose was given orally immediately after cord clamping to Group A. Syntometrine (consis...

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Bibliographic Details
Main Author: Sehrana Kousar
Format: Article
Language:English
Published: Rawalpindi Medical University 2010-06-01
Series:Journal of Rawalpindi Medical College
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Online Access:https://www.journalrmc.com/index.php/JRMC/article/view/716
Description
Summary:effects of oral misoprostol versus syntometrine for prevention of primary postpartum hemorrhage. Methods: Interventional study; Eighty patients were divided into two equal groups. Misoprostol 600 microgram single dose was given orally immediately after cord clamping to Group A. Syntometrine (consists of 10 IU oxytocin + 0.5mg ergometrine) was given intravenous to Group B. Patients were kept under observation for 6 hours. Pulse, blood pressure, temperature any need for other uterotonic drugs, estimated blood loss (<500ml or >500ml) haemoglobin percentage 6hours before and after delivery, need for blood transfusion, side effects, time and mode of delivery were noted. Results: Differences in blood pressure and transfusion were statistically insignificant between two groups. Shivering and pyrexia was more common in Group A , and nausea, vomiting and hypertension in Group B Conclusion: Like syntometrine, misoprostol can be used prophylactically orally during third stage of labour to reduce the incidence of Primary postpartum hemorrhage.
ISSN:1683-3562
1683-3570