Data on skeletal muscle apoptosis, autophagy, and morphology in mice treated with doxorubicin
Skeletal muscle apoptosis and autophagy are catabolic processes that contribute to muscle atrophy during aging, disease, and following muscle injury. In this article, we present data on skeletal muscle apoptosis, autophagy, and morphology in C57BL/6 mice following doxorubicin administration. More sp...
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doaj-a766972b351e42138a56d9670be5abcf2020-11-25T02:40:01ZengElsevierData in Brief2352-34092016-06-017786793Data on skeletal muscle apoptosis, autophagy, and morphology in mice treated with doxorubicinTroy L. Campbell0Joe Quadrilatero1Department of Kinesiology, University of Waterloo, Waterloo, Ontario, CanadaCorresponding author.; Department of Kinesiology, University of Waterloo, Waterloo, Ontario, CanadaSkeletal muscle apoptosis and autophagy are catabolic processes that contribute to muscle atrophy during aging, disease, and following muscle injury. In this article, we present data on skeletal muscle apoptosis, autophagy, and morphology in C57BL/6 mice following doxorubicin administration. More specifically, time-course data on caspase-3, caspase-8, caspase-9, calpain, and cathepsin activity are presented, along with data on ATG7, p62, LC3-I, and LC3-II protein expression. Data on skeletal muscle reactive oxygen species (ROS) production, muscle morphology, as well as body and muscle weights are also presented. Keywords: Skeletal muscle, Apoptosis, Autophagy, Doxorubicinhttp://www.sciencedirect.com/science/article/pii/S2352340916301172 |
collection |
DOAJ |
language |
English |
format |
Article |
sources |
DOAJ |
author |
Troy L. Campbell Joe Quadrilatero |
spellingShingle |
Troy L. Campbell Joe Quadrilatero Data on skeletal muscle apoptosis, autophagy, and morphology in mice treated with doxorubicin Data in Brief |
author_facet |
Troy L. Campbell Joe Quadrilatero |
author_sort |
Troy L. Campbell |
title |
Data on skeletal muscle apoptosis, autophagy, and morphology in mice treated with doxorubicin |
title_short |
Data on skeletal muscle apoptosis, autophagy, and morphology in mice treated with doxorubicin |
title_full |
Data on skeletal muscle apoptosis, autophagy, and morphology in mice treated with doxorubicin |
title_fullStr |
Data on skeletal muscle apoptosis, autophagy, and morphology in mice treated with doxorubicin |
title_full_unstemmed |
Data on skeletal muscle apoptosis, autophagy, and morphology in mice treated with doxorubicin |
title_sort |
data on skeletal muscle apoptosis, autophagy, and morphology in mice treated with doxorubicin |
publisher |
Elsevier |
series |
Data in Brief |
issn |
2352-3409 |
publishDate |
2016-06-01 |
description |
Skeletal muscle apoptosis and autophagy are catabolic processes that contribute to muscle atrophy during aging, disease, and following muscle injury. In this article, we present data on skeletal muscle apoptosis, autophagy, and morphology in C57BL/6 mice following doxorubicin administration. More specifically, time-course data on caspase-3, caspase-8, caspase-9, calpain, and cathepsin activity are presented, along with data on ATG7, p62, LC3-I, and LC3-II protein expression. Data on skeletal muscle reactive oxygen species (ROS) production, muscle morphology, as well as body and muscle weights are also presented. Keywords: Skeletal muscle, Apoptosis, Autophagy, Doxorubicin |
url |
http://www.sciencedirect.com/science/article/pii/S2352340916301172 |
work_keys_str_mv |
AT troylcampbell dataonskeletalmuscleapoptosisautophagyandmorphologyinmicetreatedwithdoxorubicin AT joequadrilatero dataonskeletalmuscleapoptosisautophagyandmorphologyinmicetreatedwithdoxorubicin |
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