Data on skeletal muscle apoptosis, autophagy, and morphology in mice treated with doxorubicin

Skeletal muscle apoptosis and autophagy are catabolic processes that contribute to muscle atrophy during aging, disease, and following muscle injury. In this article, we present data on skeletal muscle apoptosis, autophagy, and morphology in C57BL/6 mice following doxorubicin administration. More sp...

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Main Authors: Troy L. Campbell, Joe Quadrilatero
Format: Article
Language:English
Published: Elsevier 2016-06-01
Series:Data in Brief
Online Access:http://www.sciencedirect.com/science/article/pii/S2352340916301172
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spelling doaj-a766972b351e42138a56d9670be5abcf2020-11-25T02:40:01ZengElsevierData in Brief2352-34092016-06-017786793Data on skeletal muscle apoptosis, autophagy, and morphology in mice treated with doxorubicinTroy L. Campbell0Joe Quadrilatero1Department of Kinesiology, University of Waterloo, Waterloo, Ontario, CanadaCorresponding author.; Department of Kinesiology, University of Waterloo, Waterloo, Ontario, CanadaSkeletal muscle apoptosis and autophagy are catabolic processes that contribute to muscle atrophy during aging, disease, and following muscle injury. In this article, we present data on skeletal muscle apoptosis, autophagy, and morphology in C57BL/6 mice following doxorubicin administration. More specifically, time-course data on caspase-3, caspase-8, caspase-9, calpain, and cathepsin activity are presented, along with data on ATG7, p62, LC3-I, and LC3-II protein expression. Data on skeletal muscle reactive oxygen species (ROS) production, muscle morphology, as well as body and muscle weights are also presented. Keywords: Skeletal muscle, Apoptosis, Autophagy, Doxorubicinhttp://www.sciencedirect.com/science/article/pii/S2352340916301172
collection DOAJ
language English
format Article
sources DOAJ
author Troy L. Campbell
Joe Quadrilatero
spellingShingle Troy L. Campbell
Joe Quadrilatero
Data on skeletal muscle apoptosis, autophagy, and morphology in mice treated with doxorubicin
Data in Brief
author_facet Troy L. Campbell
Joe Quadrilatero
author_sort Troy L. Campbell
title Data on skeletal muscle apoptosis, autophagy, and morphology in mice treated with doxorubicin
title_short Data on skeletal muscle apoptosis, autophagy, and morphology in mice treated with doxorubicin
title_full Data on skeletal muscle apoptosis, autophagy, and morphology in mice treated with doxorubicin
title_fullStr Data on skeletal muscle apoptosis, autophagy, and morphology in mice treated with doxorubicin
title_full_unstemmed Data on skeletal muscle apoptosis, autophagy, and morphology in mice treated with doxorubicin
title_sort data on skeletal muscle apoptosis, autophagy, and morphology in mice treated with doxorubicin
publisher Elsevier
series Data in Brief
issn 2352-3409
publishDate 2016-06-01
description Skeletal muscle apoptosis and autophagy are catabolic processes that contribute to muscle atrophy during aging, disease, and following muscle injury. In this article, we present data on skeletal muscle apoptosis, autophagy, and morphology in C57BL/6 mice following doxorubicin administration. More specifically, time-course data on caspase-3, caspase-8, caspase-9, calpain, and cathepsin activity are presented, along with data on ATG7, p62, LC3-I, and LC3-II protein expression. Data on skeletal muscle reactive oxygen species (ROS) production, muscle morphology, as well as body and muscle weights are also presented. Keywords: Skeletal muscle, Apoptosis, Autophagy, Doxorubicin
url http://www.sciencedirect.com/science/article/pii/S2352340916301172
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