TRPC6 Channels Are Required for Proliferation, Migration and Invasion of Breast Cancer Cell Lines by Modulation of Orai1 and Orai3 Surface Exposure

TRPC6 Channels Are Required for Proliferation, Migration and Invasion of Breast Cancer Cell Lines by Modulation of Orai1 and Orai3 Surface Exposure

Transient receptor potential channels convey signaling information from a number of stimuli to a wide variety of cellular functions, mainly by inducing changes in cytosolic Ca2+ concentration. Different members of the TRPC, TRPM and TRPV subfamilies have been reported to play a role in tumorigenesis...

Full description

Bibliographic Details
Main Authors: Isaac Jardin, Raquel Diez-Bello, Jose J. Lopez, Pedro C. Redondo, Ginés M. Salido, Tarik Smani, Juan A. Rosado
Format: Article
Language:English
Published: MDPI AG 2018-09-01
Series:Cancers
Subjects:
TRPC6
Orai1
Orai3
store-operated calcium entry
MCF7
MDA-MB-231
Online Access:http://www.mdpi.com/2072-6694/10/9/331

Similar Items

Similar Items