The Pathogenesis of Resection-Associated Intestinal AdaptationSummary
After massive small-bowel resection, the remnant bowel compensates by a process termed adaptation. Adaptation is characterized by villus elongation and crypt deepening, which increases the capacity for absorption and digestion per unit length. The mechanisms/mediators of this important response are...
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| Format: | Article |
| Language: | English |
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Elsevier
2016-07-01
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| Series: | Cellular and Molecular Gastroenterology and Hepatology |
| Online Access: | http://www.sciencedirect.com/science/article/pii/S2352345X16300418 |
| Summary: | After massive small-bowel resection, the remnant bowel compensates by a process termed adaptation. Adaptation is characterized by villus elongation and crypt deepening, which increases the capacity for absorption and digestion per unit length. The mechanisms/mediators of this important response are multiple. The purpose of this review is to highlight the major basic contributions in elucidating a more comprehensive understanding of this process. Keywords: Adaptation, Epithelium, Angiogenesis, Absorption, Villus, Apoptosis, Proliferation, Growth Factors |
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| ISSN: | 2352-345X |