Cutaneous adverse drug reactions in a tertiary hospital in Taipei, Taiwan, in 2018
Cutaneous adverse drug reactions (CADRs) are the common adverse reactions ranging from mild self-limiting skin rash to the life-threatening severe cutaneous adverse reactions. Aims: The aim of the study was to describe the demographic characteristics of patients, different clinical patterns, and imp...
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2021-01-01
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doaj-a77a2ecd303d4848867369739544d8e92021-09-07T14:49:05ZengWolters Kluwer Medknow PublicationsJournal of Medical Sciences1011-45642021-01-01414161166:10.4103/jmedsci.jmedsci_172_19Cutaneous adverse drug reactions in a tertiary hospital in Taipei, Taiwan, in 2018Yi-Hsien ChenTzu-Ling HungHsiang-Cheng ChenJui-Hu ShihYu-Ju ChiaoLi-Ching LinChih-Tsung HungCutaneous adverse drug reactions (CADRs) are the common adverse reactions ranging from mild self-limiting skin rash to the life-threatening severe cutaneous adverse reactions. Aims: The aim of the study was to describe the demographic characteristics of patients, different clinical patterns, and implicated drugs. Methods: This was a retrospective study by analyzing the database established for all ADRs reported from January 1, 2018, to December 31, 2018, in a tertiary care teaching hospital in Taipei, Taiwan. Results: A total of 126 cases of CADRs were reported in 2018. The mean age of patients was 59.06 ± 21.63 years, with a peaking at 60–79-year-old (31.7%) and followed by 40–59-year-old (25.4%). The male-to-female ratio was 1.03:1. The most common skin reaction pattern was maculopapular eruptions (59.5%), followed by angioedema (11.9%), phlebitis (6.3%), and urticaria (6.3%). Most of the CADRs were reported with antibacterials (66.7%), followed by anti-inflammatory products (11.9%), contrast media (4.8%), and antithrombotic agents (3.2%). Conclusions: We listed the patient characteristics, each pattern of CADRs, and their associated drugs. Such information could help health-care professionals to assess CADRs and evaluate suspected drugs timely and accurately.http://www.jmedscindmc.com/article.asp?issn=1011-4564;year=2021;volume=41;issue=4;spage=161;epage=166;aulast=Chenangioedemacutaneous adverse drug reactionsmaculopapular eruptionsurticaria |
collection |
DOAJ |
language |
English |
format |
Article |
sources |
DOAJ |
author |
Yi-Hsien Chen Tzu-Ling Hung Hsiang-Cheng Chen Jui-Hu Shih Yu-Ju Chiao Li-Ching Lin Chih-Tsung Hung |
spellingShingle |
Yi-Hsien Chen Tzu-Ling Hung Hsiang-Cheng Chen Jui-Hu Shih Yu-Ju Chiao Li-Ching Lin Chih-Tsung Hung Cutaneous adverse drug reactions in a tertiary hospital in Taipei, Taiwan, in 2018 Journal of Medical Sciences angioedema cutaneous adverse drug reactions maculopapular eruptions urticaria |
author_facet |
Yi-Hsien Chen Tzu-Ling Hung Hsiang-Cheng Chen Jui-Hu Shih Yu-Ju Chiao Li-Ching Lin Chih-Tsung Hung |
author_sort |
Yi-Hsien Chen |
title |
Cutaneous adverse drug reactions in a tertiary hospital in Taipei, Taiwan, in 2018 |
title_short |
Cutaneous adverse drug reactions in a tertiary hospital in Taipei, Taiwan, in 2018 |
title_full |
Cutaneous adverse drug reactions in a tertiary hospital in Taipei, Taiwan, in 2018 |
title_fullStr |
Cutaneous adverse drug reactions in a tertiary hospital in Taipei, Taiwan, in 2018 |
title_full_unstemmed |
Cutaneous adverse drug reactions in a tertiary hospital in Taipei, Taiwan, in 2018 |
title_sort |
cutaneous adverse drug reactions in a tertiary hospital in taipei, taiwan, in 2018 |
publisher |
Wolters Kluwer Medknow Publications |
series |
Journal of Medical Sciences |
issn |
1011-4564 |
publishDate |
2021-01-01 |
description |
Cutaneous adverse drug reactions (CADRs) are the common adverse reactions ranging from mild self-limiting skin rash to the life-threatening severe cutaneous adverse reactions. Aims: The aim of the study was to describe the demographic characteristics of patients, different clinical patterns, and implicated drugs. Methods: This was a retrospective study by analyzing the database established for all ADRs reported from January 1, 2018, to December 31, 2018, in a tertiary care teaching hospital in Taipei, Taiwan. Results: A total of 126 cases of CADRs were reported in 2018. The mean age of patients was 59.06 ± 21.63 years, with a peaking at 60–79-year-old (31.7%) and followed by 40–59-year-old (25.4%). The male-to-female ratio was 1.03:1. The most common skin reaction pattern was maculopapular eruptions (59.5%), followed by angioedema (11.9%), phlebitis (6.3%), and urticaria (6.3%). Most of the CADRs were reported with antibacterials (66.7%), followed by anti-inflammatory products (11.9%), contrast media (4.8%), and antithrombotic agents (3.2%). Conclusions: We listed the patient characteristics, each pattern of CADRs, and their associated drugs. Such information could help health-care professionals to assess CADRs and evaluate suspected drugs timely and accurately. |
topic |
angioedema cutaneous adverse drug reactions maculopapular eruptions urticaria |
url |
http://www.jmedscindmc.com/article.asp?issn=1011-4564;year=2021;volume=41;issue=4;spage=161;epage=166;aulast=Chen |
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