Dissecting the common and compartment-specific features of COVID-19 severity in the lung and periphery with single-cell resolution

Summary: Severe COVID-19 is accompanied by rampant immune dysregulation in the lung and periphery, with immune cells of both compartments contributing to systemic distress. The extent to which immune cells of the lung and blood enter similar or distinct pathological states during severe disease rema...

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Bibliographic Details
Main Authors: Kalon J. Overholt, Jonathan R. Krog, Ivan Zanoni, Bryan D. Bryson
Format: Article
Language:English
Published: Elsevier 2021-07-01
Series:iScience
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2589004221007069