Dissecting the common and compartment-specific features of COVID-19 severity in the lung and periphery with single-cell resolution
Summary: Severe COVID-19 is accompanied by rampant immune dysregulation in the lung and periphery, with immune cells of both compartments contributing to systemic distress. The extent to which immune cells of the lung and blood enter similar or distinct pathological states during severe disease rema...
Main Authors: | Kalon J. Overholt, Jonathan R. Krog, Ivan Zanoni, Bryan D. Bryson |
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Format: | Article |
Language: | English |
Published: |
Elsevier
2021-07-01
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Series: | iScience |
Subjects: | |
Online Access: | http://www.sciencedirect.com/science/article/pii/S2589004221007069 |
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