Immunohistochemical expression of P16 and HER2/neu in normal oral mucosa, oral epithelial dysplasia, and oral squamous cell carcinoma
Background: Oncogenesis in the oral cavity is widely believed to result from cumulative genetic alterations that cause a transformation of the mucosa from normal to dysplastic to invasive carcinoma. The p16 gene produces p16 protein, which in turn inhibits phosphorylation of retinoblastoma (Rb), p16...
Main Authors: | , |
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Format: | Article |
Language: | English |
Published: |
College of Dentistry/ University of Baghdad
2014-06-01
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Series: | Journal of Baghdad College of Dentistry |
Online Access: | https://jbcd.uobaghdad.edu.iq/index.php/jbcd/article/view/456 |