Assessment of simplified ratio-based approaches for quantification of PET [11C]PBR28 data

Assessment of simplified ratio-based approaches for quantification of PET [11C]PBR28 data

Abstract Purpose Kinetic modelling with metabolite-corrected arterial plasma is considered the gold standard for quantification of [11C]PBR28 binding to the translocator protein (TSPO), since there is no brain region devoid of TSPO that can serve as reference. The high variability in binding observe...

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Bibliographic Details
Main Authors: Granville J. Matheson, Pontus Plavén-Sigray, Anton Forsberg, Andrea Varrone, Lars Farde, Simon Cervenka
Format: Article
Language:English
Published: SpringerOpen 2017-07-01
Series:EJNMMI Research
Subjects:
PET
TSPO
[11C]PBR28
SUVR
DVR
Online Access:http://link.springer.com/article/10.1186/s13550-017-0304-1

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http://link.springer.com/article/10.1186/s13550-017-0304-1

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