Genetic variation in human drug-related genes

Genetic variation in human drug-related genes

Abstract Background Variability in drug efficacy and adverse effects are observed in clinical practice. While the extent of genetic variability in classic pharmacokinetic genes is rather well understood, the role of genetic variation in drug targets is typically less studied. Methods Based on 60,706...

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Bibliographic Details
Main Authors: Charlotta Pauline Irmgard Schärfe, Roman Tremmel, Matthias Schwab, Oliver Kohlbacher, Debora Susan Marks
Format: Article
Language:English
Published: BMC 2017-12-01
Series:Genome Medicine
Subjects:
Bioinformatics analysis
Exome sequence analysis
Pharmacogenomics
Online Access:http://link.springer.com/article/10.1186/s13073-017-0502-5

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