The Legionella IcmSW complex directly interacts with DotL to mediate translocation of adaptor-dependent substrates.
Legionella pneumophila is a Gram-negative bacterium that replicates within human alveolar macrophages by evasion of the host endocytic pathway through the formation of a replicative vacuole. Generation of this vacuole is dependent upon the secretion of over 275 effector proteins into the host cell v...
Main Authors: | Molly C Sutherland, Thuy Linh Nguyen, Victor Tseng, Joseph P Vogel |
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Format: | Article |
Language: | English |
Published: |
Public Library of Science (PLoS)
2012-09-01
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Series: | PLoS Pathogens |
Online Access: | http://europepmc.org/articles/PMC3441705?pdf=render |
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