Multifocal choroiditis following simultaneous hepatitis A, typhoid, and yellow fever vaccination

• Main Authors: Escott S, Tarabishy AB, Davidorf FH
• Format: Article
• Language: English
• Published: Dove Medical Press 2013-02-01
• Series: Clinical Ophthalmology
• Online Access: http://www.dovepress.com/multifocal-choroiditis-following-simultaneous-hepatitis-a-typhoid-and--a12237

Sarah Escott, Ahmad B Tarabishy, Frederick H DavidorfHavener Eye Institute, The Ohio State University, Columbus, OH, USAAbstract: The paper describes the first reported case of multifocal choroiditis following simultaneous hepatitis-A, typhoid, and yellow fever vaccinations. A 33-year-old male developed sudden onset of flashing lights and floaters in his right eye 3 weeks following hepatitis A, typhoid, and yellow fever vaccinations. Fundus examination and angiography confirmed the presence of multiple peripheral chorioretinal lesions. These lesions demonstrated characteristic morphologic changes over a period of 8 weeks which were consistent with a diagnosis of self-resolving multifocal choroiditis. Vaccine-induced intraocular inflammation has been described infrequently. We demonstrate the first case of self-resolving multifocal choroiditis following simultaneous administration of hepatitis A, yellow fever, and typhoid immunizations.Keywords: multifocal choroiditis, vaccination, hepatitis A, typhoid, yellow fever