DYNLRB1 is essential for dynein mediated transport and neuronal survival

DYNLRB1 is essential for dynein mediated transport and neuronal survival

The cytoplasmic dynein motor complex transports essential signals and organelles from the cell periphery to the perinuclear region, hence is critical for the survival and function of highly polarized cells such as neurons. Dynein Light Chain Roadblock-Type 1 (DYNLRB1) is thought to be an accessory s...

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Bibliographic Details
Main Authors: Marco Terenzio, Agostina Di Pizio, Ida Rishal, Letizia Marvaldi, Pierluigi Di Matteo, Riki Kawaguchi, Giovanni Coppola, Giampietro Schiavo, Elizabeth M.C. Fisher, Mike Fainzilber
Format: Article
Language:English
Published: Elsevier 2020-07-01
Series:Neurobiology of Disease
Subjects:
dynlrb1
Dynein complex
Axonal transport
Neuronal survival
Neurodegeneration
Online Access:http://www.sciencedirect.com/science/article/pii/S0969996120300917

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