Mitochondrial Dysfunctions in Type I Endometrial Carcinoma: Exploring Their Role in Oncogenesis and Tumor Progression

Mitochondrial Dysfunctions in Type I Endometrial Carcinoma: Exploring Their Role in Oncogenesis and Tumor Progression

Type I endometrial cancer (EC) is the most common form of EC, displaying less aggressive behavior than type II. The development of type I endometrial cancer is considered a multistep process, with slow progression from normal endometrium to hyperplasia, the premalignant form, and endometrial cancer...

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Bibliographic Details
Main Authors: Clara Musicco, Gennaro Cormio, Vito Pesce, Vera Loizzi, Ettore Cicinelli, Leonardo Resta, Girolamo Ranieri, Antonella Cormio
Format: Article
Language:English
Published: MDPI AG 2018-07-01
Series:International Journal of Molecular Sciences
Subjects:
endometrial cancer
mtDNA mutations
deficit of complex I
antioxidant response
mitochondrial biogenesis
mitochondrial dynamics
mitophagy
Online Access:http://www.mdpi.com/1422-0067/19/7/2076

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