Cell-type- and region-specific restriction of neurotropic flavivirus infection by viperin

Cell-type- and region-specific restriction of neurotropic flavivirus infection by viperin

Abstract Background Flaviviruses are a group of diverse and emerging arboviruses and an immense global health problem. A number of flaviviruses are neurotropic, causing severe encephalitis and even death. Type I interferons (IFNs) are the first line of defense of the innate immune system against fla...

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Bibliographic Details
Main Authors: Richard Lindqvist, Chaitanya Kurhade, Jonathan D. Gilthorpe, Anna K. Överby
Format: Article
Language:English
Published: BMC 2018-03-01
Series:Journal of Neuroinflammation
Subjects:
Viperin
Interferon
Flavivirus
Neurons
Astrocytes
Online Access:http://link.springer.com/article/10.1186/s12974-018-1119-3

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